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Gi3 does not contribute to the inhibition of adenylate cyclase when stimulation of an alpha 2-adrenergic receptor causes activation of both Gi2 and Gi3.
McClue SJ, Selzer E, Freissmuth M, Milligan G. McClue SJ, et al. Among authors: milligan g. Biochem J. 1992 Jun 1;284 ( Pt 2)(Pt 2):565-8. doi: 10.1042/bj2840565. Biochem J. 1992. PMID: 1318036 Free PMC article.
Agonist occupancy of the alpha 2-C10 adrenergic receptor in a stable clone (1C) of Rat 1 fibroblasts produced by transfection of cells with genomic DNA encoding this receptor causes the activation of both of the pertussis-toxin-sensitive G-proteins Gi2 and Gi3 [Milligan …
Agonist occupancy of the alpha 2-C10 adrenergic receptor in a stable clone (1C) of Rat 1 fibroblasts produced by transfection of cells with …
Concurrent down-regulation of IP prostanoid receptors and the alpha-subunit of the stimulatory guanine-nucleotide-binding protein (Gs) during prolonged exposure of neuroblastoma x glioma cells to prostanoid agonists. Quantification and functional implications.
Adie EJ, Mullaney I, McKenzie FR, Milligan G. Adie EJ, et al. Among authors: milligan g. Biochem J. 1992 Jul 15;285 ( Pt 2)(Pt 2):529-36. doi: 10.1042/bj2850529. Biochem J. 1992. PMID: 1379045 Free PMC article.
The remaining receptors were capable of interacting with the stimulatory G-protein (Gs) of the adenylate cyclase cascade, as saturation analysis of the binding of [3H]PGE1 indicated that they had a similar affinity for the 3H-labelled ligand, and because the specific bindi …
The remaining receptors were capable of interacting with the stimulatory G-protein (Gs) of the adenylate cyclase cascade, as saturati …
Cholera toxin impairment of opioid-mediated inhibition of adenylate cyclase in neuroblastoma x glioma hybrid cells is due to a toxin-induced decrease in opioid receptor levels.
McKenzie FR, Milligan G. McKenzie FR, et al. Among authors: milligan g. Biochem J. 1991 Apr 1;275 ( Pt 1)(Pt 1):175-81. doi: 10.1042/bj2750175. Biochem J. 1991. PMID: 1673334 Free PMC article.
Furthermore, levels of another pertussis toxin-sensitive G-protein (Go) expressed by these cells was also not lowered by cholera toxin treatment. However, as previously noted in other cells [Milligan, Unson & Wakelam (1989) Biochem. J. 262, 643-649], marked down …
Furthermore, levels of another pertussis toxin-sensitive G-protein (Go) expressed by these cells was also not lowered by cholera toxi …
Prostanoid-mediated downregulation of Gs in NG108-15 cells.
McKenzie FR, Adie EJ, Milligan G. McKenzie FR, et al. Among authors: milligan g. Biochem Soc Trans. 1991 Apr;19(2):81S. doi: 10.1042/bst019081s. Biochem Soc Trans. 1991. PMID: 1909672 No abstract available.
792 results