Sagi I - Search Results

1

Direct photo-induced DNA strand scission by a ruthenium bipyridyl complex.

Yavin E, Stemp ED, Weiner L, Sagi I, Arad-Yellin R, Shanzer A. Yavin E, et al. Among authors: sagi i. J Inorg Biochem. 2004 Nov;98(11):1750-6. doi: 10.1016/j.jinorgbio.2004.07.016. J Inorg Biochem. 2004. PMID: 15522402

2

Antibodies targeting the catalytic zinc complex of activated matrix metalloproteinases show therapeutic potential.

Sela-Passwell N, Kikkeri R, Dym O, Rozenberg H, Margalit R, Arad-Yellin R, Eisenstein M, Brenner O, Shoham T, Danon T, Shanzer A, Sagi I. Sela-Passwell N, et al. Among authors: sagi i. Nat Med. 2011 Dec 25;18(1):143-7. doi: 10.1038/nm.2582. Nat Med. 2011. PMID: 22198278

3

Unraveling hidden regulatory sites in structurally homologous metalloproteases.

Udi Y, Fragai M, Grossman M, Mitternacht S, Arad-Yellin R, Calderone V, Melikian M, Toccafondi M, Berezovsky IN, Luchinat C, Sagi I. Udi Y, et al. Among authors: sagi i. J Mol Biol. 2013 Jul 10;425(13):2330-46. doi: 10.1016/j.jmb.2013.04.009. Epub 2013 Apr 11. J Mol Biol. 2013. PMID: 23583775

4

Structural and functional bases for allosteric control of MMP activities: can it pave the path for selective inhibition?

Sela-Passwell N, Rosenblum G, Shoham T, Sagi I. Sela-Passwell N, et al. Among authors: sagi i. Biochim Biophys Acta. 2010 Jan;1803(1):29-38. doi: 10.1016/j.bbamcr.2009.04.010. Epub 2009 May 4. Biochim Biophys Acta. 2010. PMID: 19406173 Free article. Review.

5

The intrinsic protein flexibility of endogenous protease inhibitor TIMP-1 controls its binding interface and affects its function.

Grossman M, Tworowski D, Dym O, Lee MH, Levy Y, Murphy G, Sagi I. Grossman M, et al. Among authors: sagi i. Biochemistry. 2010 Jul 27;49(29):6184-92. doi: 10.1021/bi902141x. Biochemistry. 2010. PMID: 20545310

6

Achieving broad molecular insights into dynamic protein interactions by integrated structural-kinetic approaches.

Grossman M, Sela-Passwell N, Sagi I. Grossman M, et al. Among authors: sagi i. Curr Opin Struct Biol. 2011 Oct;21(5):678-85. doi: 10.1016/j.sbi.2011.07.008. Epub 2011 Sep 22. Curr Opin Struct Biol. 2011. PMID: 21945040 Review.

7

Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody.

Udi Y, Grossman M, Solomonov I, Dym O, Rozenberg H, Moreno V, Cuniasse P, Dive V, Arroyo AG, Sagi I. Udi Y, et al. Among authors: sagi i. Structure. 2015 Jan 6;23(1):104-115. doi: 10.1016/j.str.2014.10.012. Epub 2014 Dec 4. Structure. 2015. PMID: 25482542 Free article.

8

New opportunities in drug design of metalloproteinase inhibitors: combination between structure-function experimental approaches and systems biology.

Sela-Passwell N, Trahtenherts A, Krüger A, Sagi I. Sela-Passwell N, et al. Among authors: sagi i. Expert Opin Drug Discov. 2011 May;6(5):527-42. doi: 10.1517/17460441.2011.560936. Epub 2011 Apr 21. Expert Opin Drug Discov. 2011. PMID: 22646077

9

Conformation-Specific Inhibitory Anti-MMP-7 Monoclonal Antibody Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Chemotherapeutic Cell Kill.

Mohan V, Gaffney JP, Solomonov I, Levin M, Klepfish M, Akbareian S, Grünwald B, Dym O, Eisenstein M, Yu KH, Kelsen DP, Krüger A, Edwards DR, Sagi I. Mohan V, et al. Among authors: sagi i. Cancers (Basel). 2021 Apr 2;13(7):1679. doi: 10.3390/cancers13071679. Cancers (Basel). 2021. PMID: 33918254 Free PMC article.

10

The conserved Glu-60 residue in Thermoanaerobacter brockii alcohol dehydrogenase is not essential for catalysis.

Kleifeld O, Shi SP, Zarivach R, Eisenstein M, Sagi I. Kleifeld O, et al. Among authors: sagi i. Protein Sci. 2003 Mar;12(3):468-79. doi: 10.1110/ps.0221603. Protein Sci. 2003. PMID: 12592017 Free PMC article.

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