Lee FY - Search Results

1

YC-1 [3-(5'-Hydroxymethyl-2'-furyl)-1-benzyl Indazole] exhibits a novel antiproliferative effect and arrests the cell cycle in G0-G1 in human hepatocellular carcinoma cells.

Wang SW, Pan SL, Guh JH, Chen HL, Huang DM, Chang YL, Kuo SC, Lee FY, Teng CM. Wang SW, et al. Among authors: lee fy. J Pharmacol Exp Ther. 2005 Mar;312(3):917-25. doi: 10.1124/jpet.104.077230. Epub 2004 Nov 3. J Pharmacol Exp Ther. 2005. PMID: 15525795

2

Enhancement of long-term potentiation by a potent nitric oxide-guanylyl cyclase activator, 3-(5-hydroxymethyl-2-furyl)-1-benzyl-indazole.

Chien WL, Liang KC, Teng CM, Kuo SC, Lee FY, Fu WM. Chien WL, et al. Among authors: lee fy. Mol Pharmacol. 2003 Jun;63(6):1322-8. doi: 10.1124/mol.63.6.1322. Mol Pharmacol. 2003. PMID: 12761342

3

The indazole derivative YD-3 inhibits thrombin-induced vascular smooth muscle cell proliferation and attenuates intimal thickening after balloon injury.

Peng CY, Pan SL, Guh JH, Liu YN, Chang YL, Kuo SC, Lee FY, Teng CM. Peng CY, et al. Among authors: lee fy. Thromb Haemost. 2004 Dec;92(6):1232-9. doi: 10.1160/TH04-04-0216. Thromb Haemost. 2004. PMID: 15583728

4

YC-1 [3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole] inhibits endothelial cell functions induced by angiogenic factors in vitro and angiogenesis in vivo models.

Pan SL, Guh JH, Peng CY, Wang SW, Chang YL, Cheng FC, Chang JH, Kuo SC, Lee FY, Teng CM. Pan SL, et al. Among authors: lee fy. J Pharmacol Exp Ther. 2005 Jul;314(1):35-42. doi: 10.1124/jpet.105.085126. Epub 2005 Mar 22. J Pharmacol Exp Ther. 2005. PMID: 15784655 Free article.

5

A potential role of YC-1 on the inhibition of cytokine release in peripheral blood mononuclear leukocytes and endotoxemic mouse models.

Pan SL, Guh JH, Peng CY, Chang YL, Cheng FC, Chang JH, Kuo SC, Lee FY, Teng CM. Pan SL, et al. Among authors: lee fy. Thromb Haemost. 2005 May;93(5):940-8. doi: 10.1160/TH04-03-0195. Thromb Haemost. 2005. PMID: 15886813

6

YC-1 [3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole] inhibits neointima formation in balloon-injured rat carotid through suppression of expressions and activities of matrix metalloproteinases 2 and 9.

Liu YN, Pan SL, Peng CY, Guh JH, Huang DM, Chang YL, Lin CH, Pai HC, Kuo SC, Lee FY, Teng CM. Liu YN, et al. Among authors: lee fy. J Pharmacol Exp Ther. 2006 Jan;316(1):35-41. doi: 10.1124/jpet.105.090563. Epub 2005 Sep 23. J Pharmacol Exp Ther. 2006. PMID: 16183705

7

YC-1 suppresses constitutive nuclear factor-kappaB activation and induces apoptosis in human prostate cancer cells.

Huang YT, Pan SL, Guh JH, Chang YL, Lee FY, Kuo SC, Teng CM. Huang YT, et al. Among authors: lee fy. Mol Cancer Ther. 2005 Oct;4(10):1628-35. doi: 10.1158/1535-7163.MCT-05-0090. Mol Cancer Ther. 2005. PMID: 16227413

8

Synthesis of furopyrazole analogs of 1-benzyl-3-(5-hydroxymethyl-2-furyl)indazole (YC-1) as novel anti-leukemia agents.

Chou LC, Huang LJ, Yang JS, Lee FY, Teng CM, Kuo SC. Chou LC, et al. Among authors: lee fy. Bioorg Med Chem. 2007 Feb 15;15(4):1732-40. doi: 10.1016/j.bmc.2006.12.001. Epub 2006 Dec 6. Bioorg Med Chem. 2007. PMID: 17189698

9

Anticancer mechanisms of YC-1 in human lung cancer cell line, NCI-H226.

Chen CJ, Hsu MH, Huang LJ, Yamori T, Chung JG, Lee FY, Teng CM, Kuo SC. Chen CJ, et al. Among authors: lee fy. Biochem Pharmacol. 2008 Jan 15;75(2):360-8. doi: 10.1016/j.bcp.2007.08.011. Epub 2007 Aug 17. Biochem Pharmacol. 2008. PMID: 17880926

10

The indazole derivative YD-3 specifically inhibits thrombin-induced angiogenesis in vitro and in vivo.

Peng CY, Pan SL, Pai HC, Tsai AC, Guh JH, Chang YL, Kuo SC, Lee FY, Teng CM. Peng CY, et al. Among authors: lee fy. Shock. 2010 Dec;34(6):580-5. doi: 10.1097/SHK.0b013e3181df00a3. Shock. 2010. PMID: 20351626

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