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Substituting abacavir for hyperlipidemia-associated protease inhibitors in HAART regimens improves fasting lipid profiles, maintains virologic suppression, and simplifies treatment.
Keiser PH, Sension MG, DeJesus E, Rodriguez A, Olliffe JF, Williams VC, Wakeford JH, Snidow JW, Shachoy-Clark AD, Fleming JW, Pakes GE, Hernandez JE; ESS40003 Study Team. Keiser PH, et al. Among authors: hernandez je. BMC Infect Dis. 2005 Jan 12;5:2. doi: 10.1186/1471-2334-5-2. BMC Infect Dis. 2005. PMID: 15647105 Free PMC article. Clinical Trial.
HLA-B*5701 and abacavir hypersensitivity.
Watson ME, Pimenta JM, Spreen WR, Hernandez JE. Watson ME, et al. Among authors: hernandez je. Pharmacogenetics. 2004 Nov;14(11):783-4; author reply 784. doi: 10.1097/00008571-200411000-00011. Pharmacogenetics. 2004. PMID: 15564887 No abstract available.
Lack of recurrence of hyperlactatemia in HIV-infected patients switched from stavudine to abacavir or zidovudine.
Lonergan JT, McComsey GA, Fisher RL, Shalit P, File TM Jr, Ward DJ, Williams VC, Hessenthaler SM, Lindsey L, Hernandez JE; ESS40010 (TARHEEL) Study Team. Lonergan JT, et al. Among authors: hernandez je. J Acquir Immune Defic Syndr. 2004 Aug 1;36(4):935-42. doi: 10.1097/00126334-200408010-00007. J Acquir Immune Defic Syndr. 2004. PMID: 15220700 Clinical Trial.
Improvement in lipoatrophy associated with highly active antiretroviral therapy in human immunodeficiency virus-infected patients switched from stavudine to abacavir or zidovudine: the results of the TARHEEL study.
McComsey GA, Ward DJ, Hessenthaler SM, Sension MG, Shalit P, Lonergan JT, Fisher RL, Williams VC, Hernandez JE; Trial to Assess the Regression of Hyperlactatemia and to Evaluate the Regression of Established Lipodystrophy in HIV-1-Positive Subjects (TARHEEL; ESS40010) Study Team. McComsey GA, et al. Among authors: hernandez je. Clin Infect Dis. 2004 Jan 15;38(2):263-70. doi: 10.1086/380790. Epub 2003 Dec 18. Clin Infect Dis. 2004. PMID: 14699460 Clinical Trial.
107 results