Efler SM - Search Results

1

Co-administration of CpG oligonucleotides enhances the late affinity maturation process of human anti-hepatitis B vaccine response.

Siegrist CA, Pihlgren M, Tougne C, Efler SM, Morris ML, AlAdhami MJ, Cameron DW, Cooper CL, Heathcote J, Davis HL, Lambert PH. Siegrist CA, et al. Among authors: efler sm. Vaccine. 2004 Dec 16;23(5):615-22. doi: 10.1016/j.vaccine.2004.07.014. Vaccine. 2004. PMID: 15542181 Clinical Trial.

2

Safety and immunogenicity of CPG 7909 injection as an adjuvant to Fluarix influenza vaccine.

Cooper CL, Davis HL, Morris ML, Efler SM, Krieg AM, Li Y, Laframboise C, Al Adhami MJ, Khaliq Y, Seguin I, Cameron DW. Cooper CL, et al. Among authors: efler sm. Vaccine. 2004 Aug 13;22(23-24):3136-43. doi: 10.1016/j.vaccine.2004.01.058. Vaccine. 2004. PMID: 15297066 Clinical Trial.

3

CPG 7909, an immunostimulatory TLR9 agonist oligodeoxynucleotide, as adjuvant to Engerix-B HBV vaccine in healthy adults: a double-blind phase I/II study.

Cooper CL, Davis HL, Morris ML, Efler SM, Adhami MA, Krieg AM, Cameron DW, Heathcote J. Cooper CL, et al. Among authors: efler sm. J Clin Immunol. 2004 Nov;24(6):693-701. doi: 10.1007/s10875-004-6244-3. J Clin Immunol. 2004. PMID: 15622454 Clinical Trial.

4

Induction of systemic TH1-like innate immunity in normal volunteers following subcutaneous but not intravenous administration of CPG 7909, a synthetic B-class CpG oligodeoxynucleotide TLR9 agonist.

Krieg AM, Efler SM, Wittpoth M, Al Adhami MJ, Davis HL. Krieg AM, et al. Among authors: efler sm. J Immunother. 2004 Nov-Dec;27(6):460-71. doi: 10.1097/00002371-200411000-00006. J Immunother. 2004. PMID: 15534490 Clinical Trial.

5

Phase 1B, randomized, double-blind, dose-escalation trial of CPG 10101 in patients with chronic hepatitis C virus.

McHutchison JG, Bacon BR, Gordon SC, Lawitz E, Shiffman M, Afdhal NH, Jacobson IM, Muir A, Al-Adhami M, Morris ML, Lekstrom-Himes JA, Efler SM, Davis HL. McHutchison JG, et al. Among authors: efler sm. Hepatology. 2007 Nov;46(5):1341-9. doi: 10.1002/hep.21773. Hepatology. 2007. PMID: 17929306 Clinical Trial.

6

Safety, pharmacokinetics and immune effects in normal volunteers of CPG 10101 (ACTILON), an investigational synthetic toll-like receptor 9 agonist.

Vicari AP, Schmalbach T, Lekstrom-Himes J, Morris ML, Al-Adhami MJ, Laframboise C, Leese P, Krieg AM, Efler SM, Davis HL. Vicari AP, et al. Among authors: efler sm. Antivir Ther. 2007;12(5):741-51. Antivir Ther. 2007. PMID: 17713157 Clinical Trial.

7

Immunostimulatory effects of three classes of CpG oligodeoxynucleotides on PBMC from HCV chronic carriers.

Cooper CL, Ahluwalia NK, Efler SM, Vollmer J, Krieg AM, Davis HL. Cooper CL, et al. Among authors: efler sm. J Immune Based Ther Vaccines. 2008 Jun 9;6:3. doi: 10.1186/1476-8518-6-3. J Immune Based Ther Vaccines. 2008. PMID: 18541039 Free PMC article.

8

Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs.

Krieg AM, Wu T, Weeratna R, Efler SM, Love-Homan L, Yang L, Yi AK, Short D, Davis HL. Krieg AM, et al. Among authors: efler sm. Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12631-6. doi: 10.1073/pnas.95.21.12631. Proc Natl Acad Sci U S A. 1998. PMID: 9770537 Free PMC article.

9

Quantification of oligodeoxynucleotides in human plasma with a novel hybridization assay offers greatly enhanced sensitivity over capillary gel electrophoresis.

Efler SM, Zhang L, Noll BO, Uhlmann E, Davis HL. Efler SM, et al. Oligonucleotides. 2005 Summer;15(2):119-31. doi: 10.1089/oli.2005.15.119. Oligonucleotides. 2005. PMID: 15989426

10

Designing gene therapy vectors: avoiding immune responses by using tissue-specific promoters.

Weeratna RD, Wu T, Efler SM, Zhang L, Davis HL. Weeratna RD, et al. Among authors: efler sm. Gene Ther. 2001 Dec;8(24):1872-8. doi: 10.1038/sj.gt.3301602. Gene Ther. 2001. PMID: 11821941

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