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Preparation of fully activated dendritic cells capable of priming tumor-specific cytotoxic T lymphocytes in patients with metastatic cancer using penicillin-killed streptococcus pyogenes (OK432) and anti-CD40 antibody.
Kontani K, Teramoto K, Ozaki Y, Sawai S, Tezuka N, Ishida H, Kajino K, Fujino S, Yamauchi A, Taguchi O, Kannagi R, Yokomise H, Ogasawara K. Kontani K, et al. Among authors: tezuka n. Oncol Rep. 2007 Apr;17(4):895-902. Oncol Rep. 2007. PMID: 17342333
Novel vaccination protocol consisting of injecting MUC1 DNA and nonprimed dendritic cells at the same region greatly enhanced MUC1-specific antitumor immunity in a murine model.
Kontani K, Taguchi O, Ozaki Y, Hanaoka J, Tezuka N, Sawai S, Inoue S, Fujino S, Maeda T, Itoh Y, Ogasawara K, Sato H, Ohkubo I, Kudo T. Kontani K, et al. Among authors: tezuka n. Cancer Gene Ther. 2002 Apr;9(4):330-7. doi: 10.1038/sj.cgt.7700444. Cancer Gene Ther. 2002. PMID: 11960283
Deoxyribonucleic acid (DNA) encoding a pan-major histocompatibility complex class II peptide analogue augmented antigen-specific cellular immunity and suppressive effects on tumor growth elicited by DNA vaccine immunotherapy.
Teramoto K, Kontani K, Ozaki Y, Sawai S, Tezuka N, Nagata T, Fujino S, Itoh Y, Taguchi O, Koide Y, Asai T, Ohkubo I, Ogasawara K. Teramoto K, et al. Among authors: tezuka n. Cancer Res. 2003 Nov 15;63(22):7920-5. Cancer Res. 2003. PMID: 14633722
Successful tumor eradication was achieved by collaboration of augmented cytotoxic activity and anti-angiogenic effects following therapeutic vaccines containing helper-activating analog-loaded dendritic cells and tumor antigen DNA.
Teramoto K, Kontani K, Fujita T, Ozaki Y, Sawai S, Tezuka N, Fujino S, Itoh Y, Taguchi O, Kannagi R, Ogasawara K. Teramoto K, et al. Among authors: tezuka n. Cancer Immunol Immunother. 2007 Mar;56(3):331-42. doi: 10.1007/s00262-006-0192-0. Epub 2006 Aug 5. Cancer Immunol Immunother. 2007. PMID: 16896967 Free PMC article.
118 results