Shogen K - Search Results

1

Treatment of Jurkat acute T-lymphocytic leukemia cells by onconase (Ranpirnase) is accompanied by an altered nucleocytoplasmic distribution and reduced expression of transcription factor NF-kappaB.

Tsai SY, Ardelt B, Hsieh TC, Darzynkiewicz Z, Shogen K, Wu JM. Tsai SY, et al. Among authors: shogen k. Int J Oncol. 2004 Dec;25(6):1745-52. Int J Oncol. 2004. PMID: 15547713

2

Cytostatic and cytotoxic properties of Amphinase: a novel cytotoxic ribonuclease from Rana pipiens oocytes.

Ardelt B, Ardelt W, Pozarowski P, Kunicki J, Shogen K, Darzynkiewicz Z. Ardelt B, et al. Among authors: shogen k. Cell Cycle. 2007 Dec 15;6(24):3097-102. doi: 10.4161/cc.6.24.5045. Epub 2007 Sep 12. Cell Cycle. 2007. PMID: 18073526 Free PMC article.

3

Remarkable enhancement of cytotoxicity of onconase and cepharanthine when used in combination on various tumor cell lines.

Ita M, Halicka HD, Tanaka T, Kurose A, Ardelt B, Shogen K, Darzynkiewicz Z. Ita M, et al. Among authors: shogen k. Cancer Biol Ther. 2008 Jul;7(7):1104-8. doi: 10.4161/cbt.7.7.6172. Epub 2008 Apr 19. Cancer Biol Ther. 2008. PMID: 18443430 Free PMC article.

4

The cytotoxic ribonuclease onconase targets RNA interference (siRNA).

Zhao H, Ardelt B, Ardelt W, Shogen K, Darzynkiewicz Z. Zhao H, et al. Among authors: shogen k. Cell Cycle. 2008 Oct;7(20):3258-61. doi: 10.4161/cc.7.20.6855. Epub 2008 Oct 25. Cell Cycle. 2008. PMID: 18927512 Free PMC article.

5

Mild hyperthermia predisposes tumor cells to undergo apoptosis upon treatment with onconase.

Halicka HD, Ardelt B, Shogen K, Darzynkiewicz Z. Halicka HD, et al. Among authors: shogen k. Int J Oncol. 2007 Apr;30(4):841-7. Int J Oncol. 2007. PMID: 17332922

6

Potentiation of tumor necrosis factor induced apoptosis by onconase.

Deptala A, Halicka HD, Ardelt B, Ardelt W, Mikulski SM, Shogen K, Darzynkiewicz Z. Deptala A, et al. Among authors: shogen k. Int J Oncol. 1998 Jul;13(1):11-6. doi: 10.3892/ijo.13.1.11. Int J Oncol. 1998. PMID: 9625797

7

Enhancement of activation-induced apoptosis of lymphocytes by the cytotoxic ribonuclease onconase (Ranpirnase).

Halicka DH, Pozarowski P, Ita M, Ardelt WJ, Mikulski SM, Shogen K, Darzynkiewicz Z. Halicka DH, et al. Among authors: shogen k. Int J Oncol. 2002 Dec;21(6):1245-50. doi: 10.3892/ijo.21.6.1245. Int J Oncol. 2002. PMID: 12429974

8

Onconase, an anti-tumor ribonuclease suppresses intracellular oxidative stress.

Ardelt B, Juan G, Burfeind P, Salomon T, Wu JM, Hsieh TC, Li X, Sperry R, Pozarowski P, Shogen K, Ardelt W, Darzynkiewicz Z. Ardelt B, et al. Among authors: shogen k. Int J Oncol. 2007 Sep;31(3):663-9. doi: 10.3892/ijo.31.3.663. Int J Oncol. 2007. PMID: 17671695

9

The interdependence between catalytic activity, conformational stability, and cytotoxicity of onconase.

Schulenburg C, Ardelt B, Ardelt W, Arnold U, Shogen K, Ulbrich-Hofmann R, Darzynkiewicz Z. Schulenburg C, et al. Among authors: shogen k. Cancer Biol Ther. 2007 Aug;6(8):1233-9. doi: 10.4161/cbt.6.8.4423. Epub 2007 May 11. Cancer Biol Ther. 2007. PMID: 17637563 Free article.

10

G1 arrest of U937 cells by onconase is associated with suppression of cyclin D3 expression, induction of p16INK4A, p21WAF1/CIP1 and p27KIP and decreased pRb phosphorylation.

Juan G, Ardelt B, Li X, Mikulski SM, Shogen K, Ardelt W, Mittelman A, Darzynkiewicz Z. Juan G, et al. Among authors: shogen k. Leukemia. 1998 Aug;12(8):1241-8. doi: 10.1038/sj.leu.2401100. Leukemia. 1998. PMID: 9697879

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