Cryns VL - Search Results

1

Peroxisome proliferator-activated receptor gamma agonists promote TRAIL-induced apoptosis by reducing survivin levels via cyclin D3 repression and cell cycle arrest.

Lu M, Kwan T, Yu C, Chen F, Freedman B, Schafer JM, Lee EJ, Jameson JL, Jordan VC, Cryns VL. Lu M, et al. Among authors: cryns vl. J Biol Chem. 2005 Feb 25;280(8):6742-51. doi: 10.1074/jbc.M411519200. Epub 2004 Nov 29. J Biol Chem. 2005. PMID: 15569667 Free article.

2

The small heat shock protein alpha B-crystallin negatively regulates apoptosis during myogenic differentiation by inhibiting caspase-3 activation.

Kamradt MC, Chen F, Sam S, Cryns VL. Kamradt MC, et al. Among authors: cryns vl. J Biol Chem. 2002 Oct 11;277(41):38731-6. doi: 10.1074/jbc.M201770200. Epub 2002 Jul 24. J Biol Chem. 2002. PMID: 12140279 Free article.

3

Proteolysis of the mismatch repair protein MLH1 by caspase-3 promotes DNA damage-induced apoptosis.

Chen F, Arseven OK, Cryns VL. Chen F, et al. Among authors: cryns vl. J Biol Chem. 2004 Jun 25;279(26):27542-8. doi: 10.1074/jbc.M400971200. Epub 2004 Apr 15. J Biol Chem. 2004. PMID: 15087450 Free article.

4

The small heat shock protein alpha B-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3.

Kamradt MC, Lu M, Werner ME, Kwan T, Chen F, Strohecker A, Oshita S, Wilkinson JC, Yu C, Oliver PG, Duckett CS, Buchsbaum DJ, LoBuglio AF, Jordan VC, Cryns VL. Kamradt MC, et al. Among authors: cryns vl. J Biol Chem. 2005 Mar 25;280(12):11059-66. doi: 10.1074/jbc.M413382200. Epub 2005 Jan 14. J Biol Chem. 2005. PMID: 15653686 Free article.

5

Aspirin sensitizes cancer cells to TRAIL-induced apoptosis by reducing survivin levels.

Lu M, Strohecker A, Chen F, Kwan T, Bosman J, Jordan VC, Cryns VL. Lu M, et al. Among authors: cryns vl. Clin Cancer Res. 2008 May 15;14(10):3168-76. doi: 10.1158/1078-0432.CCR-07-4362. Clin Cancer Res. 2008. PMID: 18483385

6

The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation.

Kamradt MC, Chen F, Cryns VL. Kamradt MC, et al. Among authors: cryns vl. J Biol Chem. 2001 May 11;276(19):16059-63. doi: 10.1074/jbc.C100107200. Epub 2001 Mar 23. J Biol Chem. 2001. PMID: 11274139 Free article.

7

Caspase proteolysis of the cohesin component RAD21 promotes apoptosis.

Chen F, Kamradt M, Mulcahy M, Byun Y, Xu H, McKay MJ, Cryns VL. Chen F, et al. Among authors: cryns vl. J Biol Chem. 2002 May 10;277(19):16775-81. doi: 10.1074/jbc.M201322200. Epub 2002 Mar 1. J Biol Chem. 2002. PMID: 11875078 Free article.

8

Caspase proteolysis of desmin produces a dominant-negative inhibitor of intermediate filaments and promotes apoptosis.

Chen F, Chang R, Trivedi M, Capetanaki Y, Cryns VL. Chen F, et al. Among authors: cryns vl. J Biol Chem. 2003 Feb 28;278(9):6848-53. doi: 10.1074/jbc.M212021200. Epub 2002 Dec 10. J Biol Chem. 2003. PMID: 12477713 Free article.

9

The differentiation-dependent desmosomal cadherin desmoglein 1 is a novel caspase-3 target that regulates apoptosis in keratinocytes.

Dusek RL, Getsios S, Chen F, Park JK, Amargo EV, Cryns VL, Green KJ. Dusek RL, et al. Among authors: cryns vl. J Biol Chem. 2006 Feb 10;281(6):3614-24. doi: 10.1074/jbc.M508258200. Epub 2005 Nov 14. J Biol Chem. 2006. PMID: 16286477 Free article.

10

Caspase proteolysis of the integrin beta4 subunit disrupts hemidesmosome assembly, promotes apoptosis, and inhibits cell migration.

Werner ME, Chen F, Moyano JV, Yehiely F, Jones JC, Cryns VL. Werner ME, et al. Among authors: cryns vl. J Biol Chem. 2007 Feb 23;282(8):5560-9. doi: 10.1074/jbc.M603669200. Epub 2006 Dec 18. J Biol Chem. 2007. PMID: 17178732 Free PMC article.

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