Pingoud A - Search Results

1

Interaction of DNA fragmentation factor (DFF) with DNA reveals an unprecedented mechanism for nuclease inhibition and suggests that DFF can be activated in a DNA-bound state.

Korn C, Scholz SR, Gimadutdinow O, Lurz R, Pingoud A, Meiss G. Korn C, et al. Among authors: pingoud a. J Biol Chem. 2005 Feb 18;280(7):6005-15. doi: 10.1074/jbc.M413035200. Epub 2004 Nov 30. J Biol Chem. 2005. PMID: 15572351 Free article.

2

Experimental evidence for a beta beta alpha-Me-finger nuclease motif to represent the active site of the caspase-activated DNase.

Scholz SR, Korn C, Bujnicki JM, Gimadutdinow O, Pingoud A, Meiss G. Scholz SR, et al. Among authors: pingoud a. Biochemistry. 2003 Aug 12;42(31):9288-94. doi: 10.1021/bi0348765. Biochemistry. 2003. PMID: 12899615

3

Structural and functional characterization of mitochondrial EndoG, a sugar non-specific nuclease which plays an important role during apoptosis.

Schäfer P, Scholz SR, Gimadutdinow O, Cymerman IA, Bujnicki JM, Ruiz-Carrillo A, Pingoud A, Meiss G. Schäfer P, et al. Among authors: pingoud a. J Mol Biol. 2004 Apr 23;338(2):217-28. doi: 10.1016/j.jmb.2004.02.069. J Mol Biol. 2004. PMID: 15066427 Free article.

4

Involvement of conserved histidine, lysine and tyrosine residues in the mechanism of DNA cleavage by the caspase-3 activated DNase CAD.

Korn C, Scholz SR, Gimadutdinow O, Pingoud A, Meiss G. Korn C, et al. Among authors: pingoud a. Nucleic Acids Res. 2002 Mar 15;30(6):1325-32. doi: 10.1093/nar/30.6.1325. Nucleic Acids Res. 2002. PMID: 11884629 Free PMC article.

5

The effect of ICAD-S on the formation and intracellular distribution of a nucleolytically active caspase-activated DNase.

Scholz SR, Korn C, Gimadutdinow O, Knoblauch M, Pingoud A, Meiss G. Scholz SR, et al. Among authors: pingoud a. Nucleic Acids Res. 2002 Jul 15;30(14):3045-51. doi: 10.1093/nar/gkf431. Nucleic Acids Res. 2002. PMID: 12136086 Free PMC article.

6

On the advantage of being a dimer, a case study using the dimeric Serratia nuclease and the monomeric nuclease from Anabaena sp. strain PCC 7120.

Franke I, Meiss G, Pingoud A. Franke I, et al. Among authors: pingoud a. J Biol Chem. 1999 Jan 8;274(2):825-32. doi: 10.1074/jbc.274.2.825. J Biol Chem. 1999. PMID: 9873021 Free article.

7

Sau3AI, a monomeric type II restriction endonuclease that dimerizes on the DNA and thereby induces DNA loops.

Friedhoff P, Lurz R, Lüder G, Pingoud A. Friedhoff P, et al. Among authors: pingoud a. J Biol Chem. 2001 Jun 29;276(26):23581-8. doi: 10.1074/jbc.M101694200. Epub 2001 Apr 20. J Biol Chem. 2001. PMID: 11316811 Free article.

8

Identification of functionally relevant histidine residues in the apoptotic nuclease CAD.

Meiss G, Scholz SR, Korn C, Gimadutdinow O, Pingoud A. Meiss G, et al. Among authors: pingoud a. Nucleic Acids Res. 2001 Oct 1;29(19):3901-9. doi: 10.1093/nar/29.19.3901. Nucleic Acids Res. 2001. PMID: 11574671 Free PMC article.

9

The nuclease a-inhibitor complex is characterized by a novel metal ion bridge.

Ghosh M, Meiss G, Pingoud AM, London RE, Pedersen LC. Ghosh M, et al. J Biol Chem. 2007 Feb 23;282(8):5682-90. doi: 10.1074/jbc.M605986200. Epub 2006 Nov 30. J Biol Chem. 2007. PMID: 17138564 Free PMC article.

10

Specificity changes in the evolution of type II restriction endonucleases: a biochemical and bioinformatic analysis of restriction enzymes that recognize unrelated sequences.

Pingoud V, Sudina A, Geyer H, Bujnicki JM, Lurz R, Lüder G, Morgan R, Kubareva E, Pingoud A. Pingoud V, et al. Among authors: pingoud a. J Biol Chem. 2005 Feb 11;280(6):4289-98. doi: 10.1074/jbc.M409020200. Epub 2004 Nov 24. J Biol Chem. 2005. PMID: 15563460 Free article.

How restriction enzymes with their different specificities and mode of cleavage evolved has been a long standing question in evolutionary biology. We have recently shown that several Type II restriction endonucleases, namely SsoII (downward arrow CCNGG), PspGI (downward ar …

How restriction enzymes with their different specificities and mode of cleavage evolved has been a long standing question in evolutio …

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