Saeki M - Search Results

1

Racial variability in haplotype frequencies of UGT1A1 and glucuronidation activity of a novel single nucleotide polymorphism 686C> T (P229L) found in an African-American.

Kaniwa N, Kurose K, Jinno H, Tanaka-Kagawa T, Saito Y, Saeki M, Sawada J, Tohkin M, Hasegawa R. Kaniwa N, et al. Among authors: saeki m. Drug Metab Dispos. 2005 Mar;33(3):458-65. doi: 10.1124/dmd.104.001800. Epub 2004 Nov 30. Drug Metab Dispos. 2005. PMID: 15572581

2

Glucuronidation of 7-ethyl-10-hydroxycamptothecin (SN-38), an active metabolite of irinotecan (CPT-11), by human UGT1A1 variants, G71R, P229Q, and Y486D.

Jinno H, Tanaka-Kagawa T, Hanioka N, Saeki M, Ishida S, Nishimura T, Ando M, Saito Y, Ozawa S, Sawada J. Jinno H, et al. Among authors: saeki m. Drug Metab Dispos. 2003 Jan;31(1):108-13. doi: 10.1124/dmd.31.1.108. Drug Metab Dispos. 2003. PMID: 12485959

3

Functional characterization of wild-type and variant (T202I and M59I) human UDP-glucuronosyltransferase 1A10.

Jinno H, Saeki M, Tanaka-Kagawa T, Hanioka N, Saito Y, Ozawa S, Ando M, Shirao K, Minami H, Ohtsu A, Yoshida T, Saijo N, Sawada J. Jinno H, et al. Among authors: saeki m. Drug Metab Dispos. 2003 May;31(5):528-32. doi: 10.1124/dmd.31.5.528. Drug Metab Dispos. 2003. PMID: 12695339

4

Functional characterization of human UDP-glucuronosyltransferase 1A9 variant, D256N, found in Japanese cancer patients.

Jinno H, Saeki M, Saito Y, Tanaka-Kagawa T, Hanioka N, Sai K, Kaniwa N, Ando M, Shirao K, Minami H, Ohtsu A, Yoshida T, Saijo N, Ozawa S, Sawada J. Jinno H, et al. Among authors: saeki m. J Pharmacol Exp Ther. 2003 Aug;306(2):688-93. doi: 10.1124/jpet.103.051250. Epub 2003 May 1. J Pharmacol Exp Ther. 2003. PMID: 12730278

5

Involvement of human hepatic UGT1A1, UGT2B4, and UGT2B7 in the glucuronidation of carvedilol.

Ohno A, Saito Y, Hanioka N, Jinno H, Saeki M, Ando M, Ozawa S, Sawada J. Ohno A, et al. Among authors: saeki m. Drug Metab Dispos. 2004 Feb;32(2):235-9. doi: 10.1124/dmd.32.2.235. Drug Metab Dispos. 2004. PMID: 14744946

6

UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer.

Sai K, Saeki M, Saito Y, Ozawa S, Katori N, Jinno H, Hasegawa R, Kaniwa N, Sawada J, Komamura K, Ueno K, Kamakura S, Kitakaze M, Kitamura Y, Kamatani N, Minami H, Ohtsu A, Shirao K, Yoshida T, Saijo N. Sai K, et al. Among authors: saeki m. Clin Pharmacol Ther. 2004 Jun;75(6):501-15. doi: 10.1016/j.clpt.2004.01.010. Clin Pharmacol Ther. 2004. PMID: 15179405

7

Single nucleotide polymorphisms and haplotype frequencies of UGT2B4 and UGT2B7 in a Japanese population.

Saeki M, Saito Y, Jinno H, Tanaka-Kagawa T, Ohno A, Ozawa S, Ueno K, Kamakura S, Kamatani N, Komamura K, Kitakaze M, Sawada J. Saeki M, et al. Drug Metab Dispos. 2004 Sep;32(9):1048-54. Drug Metab Dispos. 2004. PMID: 15319348

8

Genetic variations and haplotypes of UGT1A4 in a Japanese population.

Saeki M, Saito Y, Jinno H, Sai K, Hachisuka A, Kaniwa N, Ozawa S, Kawamoto M, Kamatani N, Shirao K, Minami H, Ohtsu A, Yoshida T, Saijo N, Komamura K, Kotake T, Morishita H, Kamakura S, Kitakaze M, Tomoike H, Sawada J. Saeki M, et al. Drug Metab Pharmacokinet. 2005 Apr;20(2):144-51. doi: 10.2133/dmpk.20.144. Drug Metab Pharmacokinet. 2005. PMID: 15855727 Free article.

9

Polymorphisms in the ABCC2 (cMOAT/MRP2) gene found in 72 established cell lines derived from Japanese individuals: an association between single nucleotide polymorphisms in the 5'-untranslated region and exon 28.

Itoda M, Saito Y, Soyama A, Saeki M, Murayama N, Ishida S, Sai K, Nagano M, Suzuki H, Sugiyama Y, Ozawa S, Sawada Ji J. Itoda M, et al. Among authors: saeki m. Drug Metab Dispos. 2002 Apr;30(4):363-4. doi: 10.1124/dmd.30.4.363. Drug Metab Dispos. 2002. PMID: 11901087

10

Comprehensive UGT1A1 genotyping in a Japanese population by pyrosequencing.

Saeki M, Saito Y, Jinno H, Tohkin M, Kurose K, Kaniwa N, Komamura K, Ueno K, Kamakura S, Kitakaze M, Ozawa S, Sawada J. Saeki M, et al. Clin Chem. 2003 Jul;49(7):1182-5. doi: 10.1373/49.7.1182. Clin Chem. 2003. PMID: 12816917 No abstract available.

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