Hellinga HW - Search Results

1

Orthogonal site-specific protein modification by engineering reversible thiol protection mechanisms.

Smith JJ, Conrad DW, Cuneo MJ, Hellinga HW. Smith JJ, et al. Among authors: hellinga hw. Protein Sci. 2005 Jan;14(1):64-73. doi: 10.1110/ps.04965405. Epub 2004 Dec 2. Protein Sci. 2005. PMID: 15576565 Free PMC article.

2

NMR studies of structure, hydrogen exchange, and main-chain dynamics in a disrupted-core mutant of thioredoxin.

De Lorimier R, Hellinga HW, Spicer LD. De Lorimier R, et al. Among authors: hellinga hw. Protein Sci. 1996 Dec;5(12):2552-65. doi: 10.1002/pro.5560051218. Protein Sci. 1996. PMID: 8976564 Free PMC article.

3

Protein engineering and the development of generic biosensors.

Hellinga HW, Marvin JS. Hellinga HW, et al. Trends Biotechnol. 1998 Apr;16(4):183-9. doi: 10.1016/s0167-7799(98)01174-3. Trends Biotechnol. 1998. PMID: 9586241 Review.

4

Structure-based engineering of environmentally sensitive fluorophores for monitoring protein-protein interactions.

Sloan DJ, Hellinga HW. Sloan DJ, et al. Among authors: hellinga hw. Protein Eng. 1998 Sep;11(9):819-23. doi: 10.1093/protein/11.9.819. Protein Eng. 1998. PMID: 9796832

5

Dissection of the protein G B1 domain binding site for human IgG Fc fragment.

Sloan DJ, Hellinga HW. Sloan DJ, et al. Among authors: hellinga hw. Protein Sci. 1999 Aug;8(8):1643-8. doi: 10.1110/ps.8.8.1643. Protein Sci. 1999. PMID: 10452608 Free PMC article.

6

Synthesis and characterization of a ruthenium(II)-based redox conjugate for reagentless biosensing.

Trammell SA, Goldston HM Jr, Tran PT, Tender LM, Conrad DW, Benson DE, Hellinga HW. Trammell SA, et al. Among authors: hellinga hw. Bioconjug Chem. 2001 Jul-Aug;12(4):643-7. doi: 10.1021/bc010022q. Bioconjug Chem. 2001. PMID: 11459471

7

Design of bioelectronic interfaces by exploiting hinge-bending motions in proteins.

Benson DE, Conrad DW, de Lorimier RM, Trammell SA, Hellinga HW. Benson DE, et al. Among authors: hellinga hw. Science. 2001 Aug 31;293(5535):1641-4. doi: 10.1126/science.1062461. Science. 2001. PMID: 11533486

8

Construction of a fluorescent biosensor family.

de Lorimier RM, Smith JJ, Dwyer MA, Looger LL, Sali KM, Paavola CD, Rizk SS, Sadigov S, Conrad DW, Loew L, Hellinga HW. de Lorimier RM, et al. Among authors: hellinga hw. Protein Sci. 2002 Nov;11(11):2655-75. doi: 10.1110/ps.021860. Protein Sci. 2002. PMID: 12381848 Free PMC article.

9

Computational design of receptor and sensor proteins with novel functions.

Looger LL, Dwyer MA, Smith JJ, Hellinga HW. Looger LL, et al. Among authors: hellinga hw. Nature. 2003 May 8;423(6936):185-90. doi: 10.1038/nature01556. Nature. 2003. PMID: 12736688

10

Analysis of allosteric signal transduction mechanisms in an engineered fluorescent maltose biosensor.

Dattelbaum JD, Looger LL, Benson DE, Sali KM, Thompson RB, Hellinga HW. Dattelbaum JD, et al. Among authors: hellinga hw. Protein Sci. 2005 Feb;14(2):284-91. doi: 10.1110/ps.041146005. Protein Sci. 2005. PMID: 15659363 Free PMC article.

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