Conaway JW - Search Results

1

VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.

Kamura T, Maenaka K, Kotoshiba S, Matsumoto M, Kohda D, Conaway RC, Conaway JW, Nakayama KI. Kamura T, et al. Among authors: conaway jw, conaway rc. Genes Dev. 2004 Dec 15;18(24):3055-65. doi: 10.1101/gad.1252404. Genes Dev. 2004. PMID: 15601820 Free PMC article.

2

Roles of SCF and VHL ubiquitin ligases in regulation of cell growth.

Kamura T, Conaway JW, Conaway RC. Kamura T, et al. Among authors: conaway jw, conaway rc. Prog Mol Subcell Biol. 2002;29:1-15. doi: 10.1007/978-3-642-56373-7_1. Prog Mol Subcell Biol. 2002. PMID: 11908068 Review. No abstract available.

3

A molecular basis for stabilization of the von Hippel-Lindau (VHL) tumor suppressor protein by components of the VHL ubiquitin ligase.

Kamura T, Brower CS, Conaway RC, Conaway JW. Kamura T, et al. Among authors: conaway jw, conaway rc. J Biol Chem. 2002 Aug 16;277(33):30388-93. doi: 10.1074/jbc.M203344200. Epub 2002 Jun 4. J Biol Chem. 2002. PMID: 12048197 Free article.

4

The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2.

Kamura T, Conrad MN, Yan Q, Conaway RC, Conaway JW. Kamura T, et al. Among authors: conaway jw, conaway rc. Genes Dev. 1999 Nov 15;13(22):2928-33. doi: 10.1101/gad.13.22.2928. Genes Dev. 1999. PMID: 10579999 Free PMC article.

5

Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase.

Brower CS, Sato S, Tomomori-Sato C, Kamura T, Pause A, Stearman R, Klausner RD, Malik S, Lane WS, Sorokina I, Roeder RG, Conaway JW, Conaway RC. Brower CS, et al. Among authors: conaway jw, conaway rc. Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10353-8. doi: 10.1073/pnas.162424199. Epub 2002 Jul 29. Proc Natl Acad Sci U S A. 2002. PMID: 12149480 Free PMC article.

6

Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases.

Mahrour N, Redwine WB, Florens L, Swanson SK, Martin-Brown S, Bradford WD, Staehling-Hampton K, Washburn MP, Conaway RC, Conaway JW. Mahrour N, et al. Among authors: conaway jw, conaway rc. J Biol Chem. 2008 Mar 21;283(12):8005-13. doi: 10.1074/jbc.M706987200. Epub 2008 Jan 10. J Biol Chem. 2008. PMID: 18187417 Free article.

7

Elongin (SIII): a multisubunit regulator of elongation by RNA polymerase II.

Aso T, Lane WS, Conaway JW, Conaway RC. Aso T, et al. Among authors: conaway jw, conaway rc. Science. 1995 Sep 8;269(5229):1439-43. doi: 10.1126/science.7660129. Science. 1995. PMID: 7660129

8

Characterization of elongin C functional domains required for interaction with elongin B and activation of elongin A.

Takagi Y, Conaway RC, Conaway JW. Takagi Y, et al. Among authors: conaway jw, conaway rc. J Biol Chem. 1996 Oct 11;271(41):25562-8. doi: 10.1074/jbc.271.41.25562. J Biol Chem. 1996. PMID: 8810329 Free article.

9

Identification of elongin C sequences required for interaction with the von Hippel-Lindau tumor suppressor protein.

Takagi Y, Pause A, Conaway RC, Conaway JW. Takagi Y, et al. Among authors: conaway jw, conaway rc. J Biol Chem. 1997 Oct 24;272(43):27444-9. doi: 10.1074/jbc.272.43.27444. J Biol Chem. 1997. PMID: 9341197 Free article.

10

The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families.

Kamura T, Sato S, Haque D, Liu L, Kaelin WG Jr, Conaway RC, Conaway JW. Kamura T, et al. Among authors: conaway jw, conaway rc. Genes Dev. 1998 Dec 15;12(24):3872-81. doi: 10.1101/gad.12.24.3872. Genes Dev. 1998. PMID: 9869640 Free PMC article.

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