von Kügelgen I - Search Results

1

Evidence for the functional expression and pharmacological characterization of adenine receptors in native cells and tissues.

Gorzalka S, Vittori S, Volpini R, Cristalli G, von Kügelgen I, Müller CE. Gorzalka S, et al. Among authors: von kugelgen i. Mol Pharmacol. 2005 Mar;67(3):955-64. doi: 10.1124/mol.104.006601. Epub 2004 Dec 16. Mol Pharmacol. 2005. PMID: 15604413

2

Cloning and functional expression of a novel Gi protein-coupled receptor for adenine from mouse brain.

von Kügelgen I, Schiedel AC, Hoffmann K, Alsdorf BB, Abdelrahman A, Müller CE. von Kügelgen I, et al. Mol Pharmacol. 2008 Feb;73(2):469-77. doi: 10.1124/mol.107.037069. Epub 2007 Nov 1. Mol Pharmacol. 2008. PMID: 17975009

3

Interaction of new, very potent non-nucleotide antagonists with Arg256 of the human platelet P2Y12 receptor.

Hoffmann K, Baqi Y, Morena MS, Glänzel M, Müller CE, von Kügelgen I. Hoffmann K, et al. Among authors: von kugelgen i. J Pharmacol Exp Ther. 2009 Nov;331(2):648-55. doi: 10.1124/jpet.109.156687. Epub 2009 Aug 18. J Pharmacol Exp Ther. 2009. PMID: 19690189

4

The rat adenine receptor: pharmacological characterization and mutagenesis studies to investigate its putative ligand binding site.

Knospe M, Müller CE, Rosa P, Abdelrahman A, von Kügelgen I, Thimm D, Schiedel AC. Knospe M, et al. Among authors: von kugelgen i. Purinergic Signal. 2013 Sep;9(3):367-81. doi: 10.1007/s11302-013-9355-6. Epub 2013 Feb 15. Purinergic Signal. 2013. PMID: 23413038 Free PMC article.

5

Characterization of new G protein-coupled adenine receptors in mouse and hamster.

Thimm D, Knospe M, Abdelrahman A, Moutinho M, Alsdorf BB, von Kügelgen I, Schiedel AC, Müller CE. Thimm D, et al. Among authors: von kugelgen i. Purinergic Signal. 2013 Sep;9(3):415-26. doi: 10.1007/s11302-013-9360-9. Epub 2013 Apr 23. Purinergic Signal. 2013. PMID: 23608776 Free PMC article.

6

Competitive mode and site of interaction of ticagrelor at the human platelet P2Y12 -receptor.

Hoffmann K, Lutz DA, Straßburger J, Baqi Y, Müller CE, von Kügelgen I. Hoffmann K, et al. Among authors: von kugelgen i. J Thromb Haemost. 2014 Nov;12(11):1898-905. doi: 10.1111/jth.12719. Epub 2014 Sep 29. J Thromb Haemost. 2014. PMID: 25186974 Free article.

7

Diindolylmethane Derivatives: Potent Agonists of the Immunostimulatory Orphan G Protein-Coupled Receptor GPR84.

Pillaiyar T, Köse M, Sylvester K, Weighardt H, Thimm D, Borges G, Förster I, von Kügelgen I, Müller CE. Pillaiyar T, et al. Among authors: von kugelgen i. J Med Chem. 2017 May 11;60(9):3636-3655. doi: 10.1021/acs.jmedchem.6b01593. Epub 2017 May 1. J Med Chem. 2017. PMID: 28406627

8

Key determinants of nucleotide-activated G protein-coupled P2Y(2) receptor function revealed by chemical and pharmacological experiments, mutagenesis and homology modeling.

Hillmann P, Ko GY, Spinrath A, Raulf A, von Kügelgen I, Wolff SC, Nicholas RA, Kostenis E, Höltje HD, Müller CE. Hillmann P, et al. Among authors: von kugelgen i. J Med Chem. 2009 May 14;52(9):2762-75. doi: 10.1021/jm801442p. J Med Chem. 2009. PMID: 19419204

9

Central P2Y12 receptor blockade alleviates inflammatory and neuropathic pain and cytokine production in rodents.

Horváth G, Gölöncsér F, Csölle C, Király K, Andó RD, Baranyi M, Koványi B, Máté Z, Hoffmann K, Algaier I, Baqi Y, Müller CE, Von Kügelgen I, Sperlágh B. Horváth G, et al. Among authors: von kugelgen i. Neurobiol Dis. 2014 Oct;70:162-78. doi: 10.1016/j.nbd.2014.06.011. Epub 2014 Jun 25. Neurobiol Dis. 2014. PMID: 24971933 Free PMC article.

10

6-(Ar)Alkylamino-Substituted Uracil Derivatives: Lipid Mimetics with Potent Activity at the Orphan G Protein-Coupled Receptor 84 (GPR84).

Pillaiyar T, Köse M, Namasivayam V, Sylvester K, Borges G, Thimm D, von Kügelgen I, Müller CE. Pillaiyar T, et al. Among authors: von kugelgen i. ACS Omega. 2018 Mar 31;3(3):3365-3383. doi: 10.1021/acsomega.7b02092. Epub 2018 Mar 20. ACS Omega. 2018. PMID: 30023867 Free PMC article.

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