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Microvascular patterning is controlled by fine-tuning the Akt signal.
Sun JF, Phung T, Shiojima I, Felske T, Upalakalin JN, Feng D, Kornaga T, Dor T, Dvorak AM, Walsh K, Benjamin LE. Sun JF, et al. Among authors: benjamin le. Proc Natl Acad Sci U S A. 2005 Jan 4;102(1):128-33. doi: 10.1073/pnas.0403198102. Epub 2004 Dec 20. Proc Natl Acad Sci U S A. 2005. PMID: 15611473 Free PMC article.
Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin.
Phung TL, Ziv K, Dabydeen D, Eyiah-Mensah G, Riveros M, Perruzzi C, Sun J, Monahan-Earley RA, Shiojima I, Nagy JA, Lin MI, Walsh K, Dvorak AM, Briscoe DM, Neeman M, Sessa WC, Dvorak HF, Benjamin LE. Phung TL, et al. Among authors: benjamin le. Cancer Cell. 2006 Aug;10(2):159-70. doi: 10.1016/j.ccr.2006.07.003. Cancer Cell. 2006. PMID: 16904613 Free PMC article.
Survival mechanisms of VEGF and PlGF during microvascular remodeling.
Upalakalin JN, Hemo I, Dehio C, Keshet E, Benjamin LE. Upalakalin JN, et al. Among authors: benjamin le. Cold Spring Harb Symp Quant Biol. 2002;67:181-7. doi: 10.1101/sqb.2002.67.181. Cold Spring Harb Symp Quant Biol. 2002. PMID: 12858539 Review. No abstract available.
86 results