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Functionalization of tumor necrosis factor-alpha using phage display technique and PEGylation improves its antitumor therapeutic window.
Shibata H, Yoshioka Y, Ikemizu S, Kobayashi K, Yamamoto Y, Mukai Y, Okamoto T, Taniai M, Kawamura M, Abe Y, Nakagawa S, Hayakawa T, Nagata S, Yamagata Y, Mayumi T, Kamada H, Tsutsumi Y. Shibata H, et al. Among authors: kawamura m. Clin Cancer Res. 2004 Dec 15;10(24):8293-300. doi: 10.1158/1078-0432.CCR-04-0770. Clin Cancer Res. 2004. PMID: 15623605
Optimal site-specific PEGylation of mutant TNF-alpha improves its antitumor potency.
Yoshioka Y, Tsutsumi Y, Ikemizu S, Yamamoto Y, Shibata H, Nishibata T, Mukai Y, Okamoto T, Taniai M, Kawamura M, Abe Y, Nakagawa S, Nagata S, Yamagata Y, Mayumi T. Yoshioka Y, et al. Among authors: kawamura m. Biochem Biophys Res Commun. 2004 Mar 19;315(4):808-14. doi: 10.1016/j.bbrc.2004.01.125. Biochem Biophys Res Commun. 2004. PMID: 14985084
Optimal construction of non-immune scFv phage display libraries from mouse bone marrow and spleen established to select specific scFvs efficiently binding to antigen.
Okamoto T, Mukai Y, Yoshioka Y, Shibata H, Kawamura M, Yamamoto Y, Nakagawa S, Kamada H, Hayakawa T, Mayumi T, Tsutsumi Y. Okamoto T, et al. Among authors: kawamura m. Biochem Biophys Res Commun. 2004 Oct 15;323(2):583-91. doi: 10.1016/j.bbrc.2004.08.131. Biochem Biophys Res Commun. 2004. PMID: 15369791
A novel method for construction of gene fragment library to searching epitopes.
Kawamura M, Shibata H, Kamada H, Okamoto T, Mukai Y, Sugita T, Abe Y, Imai S, Nomura T, Nagano K, Mayumi T, Nakagawa S, Tsutsumi Y, Tsunoda SI. Kawamura M, et al. Biochem Biophys Res Commun. 2006 Jul 21;346(1):198-204. doi: 10.1016/j.bbrc.2006.05.103. Epub 2006 May 24. Biochem Biophys Res Commun. 2006. PMID: 16759645
Creation of novel cell-penetrating peptides for intracellular drug delivery using systematic phage display technology originated from Tat transduction domain.
Kamada H, Okamoto T, Kawamura M, Shibata H, Abe Y, Ohkawa A, Nomura T, Sato M, Mukai Y, Sugita T, Imai S, Nagano K, Tsutsumi Y, Nakagawa S, Mayumi T, Tsunoda S. Kamada H, et al. Among authors: kawamura m. Biol Pharm Bull. 2007 Feb;30(2):218-23. doi: 10.1248/bpb.30.218. Biol Pharm Bull. 2007. PMID: 17268054 Free article.
Production of functional human alpha 1-antitrypsin by plant cell culture.
Terashima M, Murai Y, Kawamura M, Nakanishi S, Stoltz T, Chen L, Drohan W, Rodriguez RL, Katoh S. Terashima M, et al. Among authors: kawamura m. Appl Microbiol Biotechnol. 1999 Oct;52(4):516-23. doi: 10.1007/s002530051554. Appl Microbiol Biotechnol. 1999. PMID: 10570799
2,629 results