Ernst M - Search Results

1

The threshold of gp130-dependent STAT3 signaling is critical for normal regulation of hematopoiesis.

Jenkins BJ, Roberts AW, Najdovska M, Grail D, Ernst M. Jenkins BJ, et al. Among authors: ernst m. Blood. 2005 May 1;105(9):3512-20. doi: 10.1182/blood-2004-09-3751. Epub 2005 Jan 13. Blood. 2005. PMID: 15650055 Free article.

2

Gp130-mediated signal transduction in embryonic stem cells involves activation of Jak and Ras/mitogen-activated protein kinase pathways.

Ernst M, Oates A, Dunn AR. Ernst M, et al. J Biol Chem. 1996 Nov 22;271(47):30136-43. doi: 10.1074/jbc.271.47.30136. J Biol Chem. 1996. PMID: 8939963 Free article.

3

The carboxyl-terminal domains of gp130-related cytokine receptors are necessary for suppressing embryonic stem cell differentiation. Involvement of STAT3.

Ernst M, Novak U, Nicholson SE, Layton JE, Dunn AR. Ernst M, et al. J Biol Chem. 1999 Apr 2;274(14):9729-37. doi: 10.1074/jbc.274.14.9729. J Biol Chem. 1999. PMID: 10092661 Free article.

4

Defective gp130-mediated signal transducer and activator of transcription (STAT) signaling results in degenerative joint disease, gastrointestinal ulceration, and failure of uterine implantation.

Ernst M, Inglese M, Waring P, Campbell IK, Bao S, Clay FJ, Alexander WS, Wicks IP, Tarlinton DM, Novak U, Heath JK, Dunn AR. Ernst M, et al. J Exp Med. 2001 Jul 16;194(2):189-203. doi: 10.1084/jem.194.2.189. J Exp Med. 2001. PMID: 11457894 Free PMC article.

5

Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice.

Tebbutt NC, Giraud AS, Inglese M, Jenkins B, Waring P, Clay FJ, Malki S, Alderman BM, Grail D, Hollande F, Heath JK, Ernst M. Tebbutt NC, et al. Among authors: ernst m. Nat Med. 2002 Oct;8(10):1089-97. doi: 10.1038/nm763. Epub 2002 Sep 9. Nat Med. 2002. PMID: 12219085

6

Hematopoietic abnormalities in mice deficient in gp130-mediated STAT signaling.

Jenkins BJ, Quilici C, Roberts AW, Grail D, Dunn AR, Ernst M. Jenkins BJ, et al. Among authors: ernst m. Exp Hematol. 2002 Nov;30(11):1248-56. doi: 10.1016/s0301-472x(02)00929-3. Exp Hematol. 2002. PMID: 12423677 Free article.

7

The role of gp130/IL-6 cytokines in the development of pulmonary fibrosis: critical determinants of disease susceptibility and progression?

Knight DA, Ernst M, Anderson GP, Moodley YP, Mutsaers SE. Knight DA, et al. Among authors: ernst m. Pharmacol Ther. 2003 Sep;99(3):327-38. doi: 10.1016/s0163-7258(03)00095-0. Pharmacol Ther. 2003. PMID: 12951164

8

Threshold effects of glucose transporter-4 (GLUT4) deficiency on cardiac glucose uptake and development of hypertrophy.

Kaczmarczyk SJ, Andrikopoulos S, Favaloro J, Domenighetti AA, Dunn A, Ernst M, Grail D, Fodero-Tavoletti M, Huggins CE, Delbridge LM, Zajac JD, Proietto J. Kaczmarczyk SJ, et al. Among authors: ernst m. J Mol Endocrinol. 2003 Dec;31(3):449-59. doi: 10.1677/jme.0.0310449. J Mol Endocrinol. 2003. PMID: 14664706

9

Acquiring signalling specificity from the cytokine receptor gp130.

Ernst M, Jenkins BJ. Ernst M, et al. Trends Genet. 2004 Jan;20(1):23-32. doi: 10.1016/j.tig.2003.11.003. Trends Genet. 2004. PMID: 14698616 Review.

10

Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130.

Judd LM, Alderman BM, Howlett M, Shulkes A, Dow C, Moverley J, Grail D, Jenkins BJ, Ernst M, Giraud AS. Judd LM, et al. Among authors: ernst m. Gastroenterology. 2004 Jan;126(1):196-207. doi: 10.1053/j.gastro.2003.10.066. Gastroenterology. 2004. PMID: 14699500

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