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Detection of native peptides as potent inhibitors of enzymes. Crystal structure of the complex formed between treated bovine alpha-chymotrypsin and an autocatalytically produced fragment, IIe-Val-Asn-Gly-Glu-Glu-Ala-Val-Pro-Gly-Ser-Trp-Pro-Trp, at 2.2 angstroms resolution.
Singh N, Jabeen T, Sharma S, Roy I, Gupta MN, Bilgrami S, Somvanshi RK, Dey S, Perbandt M, Betzel C, Srinivasan A, Singh TP. Singh N, et al. Among authors: srinivasan a. FEBS J. 2005 Jan;272(2):562-72. doi: 10.1111/j.1742-4658.2004.04499.x. FEBS J. 2005. PMID: 15654893 Free article.
Design of specific peptide inhibitors for group I phospholipase A2: structure of a complex formed between phospholipase A2 from Naja naja sagittifera (group I) and a designed peptide inhibitor Val-Ala-Phe-Arg-Ser (VAFRS) at 1.9 A resolution reveals unique features.
Singh RK, Vikram P, Makker J, Jabeen T, Sharma S, Dey S, Kaur P, Srinivasan A, Singh TP. Singh RK, et al. Among authors: srinivasan a. Biochemistry. 2003 Oct 14;42(40):11701-6. doi: 10.1021/bi035076x. Biochemistry. 2003. PMID: 14529280
Specific binding of non-steroidal anti-inflammatory drugs (NSAIDs) to phospholipase A2: structure of the complex formed between phospholipase A2 and diclofenac at 2.7 A resolution.
Singh N, Jabeen T, Sharma S, Somvanshi RK, Dey S, Srinivasan A, Singh TP. Singh N, et al. Among authors: srinivasan a. Acta Crystallogr D Biol Crystallogr. 2006 Apr;62(Pt 4):410-6. doi: 10.1107/S0907444906003660. Epub 2006 Mar 18. Acta Crystallogr D Biol Crystallogr. 2006. PMID: 16552142
Crystal structure of lactoperoxidase at 2.4 A resolution.
Singh AK, Singh N, Sharma S, Singh SB, Kaur P, Bhushan A, Srinivasan A, Singh TP. Singh AK, et al. Among authors: srinivasan a. J Mol Biol. 2008 Feb 29;376(4):1060-75. doi: 10.1016/j.jmb.2007.12.012. Epub 2007 Dec 14. J Mol Biol. 2008. PMID: 18191143
Crystal structure of a heterodimer of phospholipase A2 from Naja naja sagittifera at 2.3 A resolution reveals the presence of a new PLA2-like protein with a novel cys 32-Cys 49 disulphide bridge with a bound sugar at the substrate-binding site.
Jabeen T, Singh N, Singh RK, Jasti J, Sharma S, Kaur P, Srinivasan A, Singh TP. Jabeen T, et al. Among authors: srinivasan a. Proteins. 2006 Feb 1;62(2):329-37. doi: 10.1002/prot.20708. Proteins. 2006. PMID: 16287060
Structure of the buffalo secretory signalling glycoprotein at 2.8 A resolution.
Ethayathulla AS, Srivastava DB, Kumar J, Saravanan K, Bilgrami S, Sharma S, Kaur P, Srinivasan A, Singh TP. Ethayathulla AS, et al. Among authors: srinivasan a. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Apr 1;63(Pt 4):258-65. doi: 10.1107/S1744309107010445. Epub 2007 Mar 12. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007. PMID: 17401190 Free PMC article.
1,955 results