Johnson K - Search Results

1

Synergistic interactions between imatinib mesylate and the novel phosphoinositide-dependent kinase-1 inhibitor OSU-03012 in overcoming imatinib mesylate resistance.

Tseng PH, Lin HP, Zhu J, Chen KF, Hade EM, Young DC, Byrd JC, Grever M, Johnson K, Druker BJ, Chen CS. Tseng PH, et al. Among authors: johnson k. Blood. 2005 May 15;105(10):4021-7. doi: 10.1182/blood-2004-07-2967. Epub 2005 Jan 21. Blood. 2005. PMID: 15665113 Free PMC article.

2

Interactions of p62(dok) with p210(bcr-abl) and Bcr-Abl-associated proteins.

Bhat A, Johnson KJ, Oda T, Corbin AS, Druker BJ. Bhat A, et al. Among authors: johnson kj. J Biol Chem. 1998 Nov 27;273(48):32360-8. doi: 10.1074/jbc.273.48.32360. J Biol Chem. 1998. PMID: 9822717 Free article.

3

In vitro studies of the combination of imatinib mesylate (Gleevec) and arsenic trioxide (Trisenox) in chronic myelogenous leukemia.

La Rosée P, Johnson K, O'Dwyer ME, Druker BJ. La Rosée P, et al. Among authors: johnson k. Exp Hematol. 2002 Jul;30(7):729-37. doi: 10.1016/s0301-472x(02)00836-6. Exp Hematol. 2002. PMID: 12135670 Free article.

4

In vitro efficacy of combined treatment depends on the underlying mechanism of resistance in imatinib-resistant Bcr-Abl-positive cell lines.

La Rosée P, Johnson K, Corbin AS, Stoffregen EP, Moseson EM, Willis S, Mauro MM, Melo JV, Deininger MW, Druker BJ. La Rosée P, et al. Among authors: johnson k. Blood. 2004 Jan 1;103(1):208-15. doi: 10.1182/blood-2003-04-1074. Epub 2003 Aug 21. Blood. 2004. PMID: 12933582 Free article.

5

Coexistence of phosphotyrosine-dependent and -independent interactions between Cbl and Bcr-Abl.

Gaston I, Johnson KJ, Oda T, Bhat A, Reis M, Langdon W, Shen L, Deininger MW, Druker BJ. Gaston I, et al. Exp Hematol. 2004 Jan;32(1):113-21. doi: 10.1016/j.exphem.2003.09.018. Exp Hematol. 2004. PMID: 14725908 Free article.

6

Comparison of imatinib mesylate, dasatinib (BMS-354825), and nilotinib (AMN107) in an N-ethyl-N-nitrosourea (ENU)-based mutagenesis screen: high efficacy of drug combinations.

Bradeen HA, Eide CA, O'Hare T, Johnson KJ, Willis SG, Lee FY, Druker BJ, Deininger MW. Bradeen HA, et al. Blood. 2006 Oct 1;108(7):2332-8. doi: 10.1182/blood-2006-02-004580. Epub 2006 Jun 13. Blood. 2006. PMID: 16772610 Free PMC article.

7

Kinase domain mutants of Bcr-Abl exhibit altered transformation potency, kinase activity, and substrate utilization, irrespective of sensitivity to imatinib.

Griswold IJ, MacPartlin M, Bumm T, Goss VL, O'Hare T, Lee KA, Corbin AS, Stoffregen EP, Smith C, Johnson K, Moseson EM, Wood LJ, Polakiewicz RD, Druker BJ, Deininger MW. Griswold IJ, et al. Among authors: johnson k. Mol Cell Biol. 2006 Aug;26(16):6082-93. doi: 10.1128/MCB.02202-05. Mol Cell Biol. 2006. PMID: 16880519 Free PMC article.

8

A BCR-ABL mutant lacking direct binding sites for the GRB2, CBL and CRKL adapter proteins fails to induce leukemia in mice.

Johnson KJ, Griswold IJ, O'Hare T, Corbin AS, Loriaux M, Deininger MW, Druker BJ. Johnson KJ, et al. PLoS One. 2009 Oct 13;4(10):e7439. doi: 10.1371/journal.pone.0007439. PLoS One. 2009. PMID: 19823681 Free PMC article.

9

Threshold levels of ABL tyrosine kinase inhibitors retained in chronic myeloid leukemia cells determine their commitment to apoptosis.

O'Hare T, Eide CA, Agarwal A, Adrian LT, Zabriskie MS, Mackenzie RJ, Latocha DH, Johnson KJ, You H, Luo J, Riddle SM, Marks BD, Vogel KW, Koop DR, Apgar J, Tyner JW, Deininger MW, Druker BJ. O'Hare T, et al. Cancer Res. 2013 Jun 1;73(11):3356-70. doi: 10.1158/0008-5472.CAN-12-3904. Epub 2013 Apr 10. Cancer Res. 2013. PMID: 23576564 Free PMC article.

10

YM155 potently kills acute lymphoblastic leukemia cells through activation of the DNA damage pathway.

Chang BH, Johnson K, LaTocha D, Rowley JS, Bryant J, Burke R, Smith RL, Loriaux M, Müschen M, Mullighan C, Druker BJ, Tyner JW. Chang BH, et al. Among authors: johnson k. J Hematol Oncol. 2015 Apr 22;8:39. doi: 10.1186/s13045-015-0132-6. J Hematol Oncol. 2015. PMID: 25895498 Free PMC article.

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