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269 results

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Discovery of PF-07265028, A Selective Small Molecule Inhibitor of Hematopoietic Progenitor Kinase 1 (HPK1) for the Treatment of Cancer.
Gallego RA, Cho-Schultz S, Del Bel M, Dechert-Schmitt AM, Donaldson JS, He M, Jalaie M, Kania R, Matthews J, McTigue M, Tuttle JB, Risley H, Zhou D, Zhou R, Ahmad OK, Bernier L, Berritt S, Braganza J, Chen Z, Cianfrogna JA, Collins M, Costa Jones C, Cronin CN, Davis C, Dress K, Edwards M, Farrell W, France SP, Grable N, Johnson E, Johnson TW, Jones R, Knauber T, Lafontaine J, Loach RP, Maestre M, Miller N, Moen M, Monfette S, Morse P, Nager AR, Niosi M, Richardson P, Rohner AK, Sach NW, Timofeevski S, Tucker JW, Vetelino B, Zhang L, Nair SK. Gallego RA, et al. Among authors: johnson tw. J Med Chem. 2024 Dec 26;67(24):22002-22038. doi: 10.1021/acs.jmedchem.4c01930. Epub 2024 Dec 9. J Med Chem. 2024. PMID: 39651809 Clinical Trial.
Discovery of Highly Selective Inhibitors of Microtubule-Associated Serine/Threonine Kinase-like (MASTL).
Gallego RA, Scales S, Toledo C, Auth M, Bernier L, Berry M, Brun S, Chung L, Davis C, Diehl W, Dress K, Eisele K, Elleraas J, Ewanicki J, Fobian Y, Greasley S, Greenwald EC, Johnson TW, Khamphavong P, Lafontaine J, Li J, Linton A, Maestre M, Miller N, Murtaza A, Patman RL, Quinlan CL, Ramms DJ, Richardson P, Sach N, Salomon-Ferrer R, Silva F, Timofeevski S, Tran P, Tran-Dubé M, Wang F, Wang W, Wythes M, Yang S, Zou A, VanArsdale T, McAlpine I. Gallego RA, et al. Among authors: johnson tw. J Med Chem. 2024 Nov 14;67(21):19234-19246. doi: 10.1021/acs.jmedchem.4c01659. Epub 2024 Nov 5. J Med Chem. 2024. PMID: 39499084
Wavelet and time-based cerebral autoregulation analysis using diffuse correlation spectroscopy on adults undergoing extracorporeal membrane oxygenation therapy.
Dar IA, Khan IR, Johnson TW, Helmy SM, Cardona JI, Escobar S, Selioutski O, Marinescu MA, Zhang CT, Proctor AR, AbdAllah N, Busch DR, Maddox RK, Choe R. Dar IA, et al. Among authors: johnson tw. PLoS One. 2024 Oct 29;19(10):e0299752. doi: 10.1371/journal.pone.0299752. eCollection 2024. PLoS One. 2024. PMID: 39471182 Free PMC article.
Impact of lesion morphology on stent elongation during bifurcation PCI: an in vivo OCT study.
McGarvey M, Lam LT, Razak MA, Barraclough J, O'Gallagher K, Webb I, Melikian N, Kalra S, MacCarthy P, Shah AM, Hill JM, Johnson TW, Byrne J, Dworakowski R, Pareek N. McGarvey M, et al. Among authors: johnson tw. EuroIntervention. 2024 Sep 16;20(18):e1184-e1194. doi: 10.4244/EIJ-D-23-00663. EuroIntervention. 2024. PMID: 39279513 Free article.
269 results