Adams J - Search Results

1

Small molecule inhibitors of IkappaB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling.

Lam LT, Davis RE, Pierce J, Hepperle M, Xu Y, Hottelet M, Nong Y, Wen D, Adams J, Dang L, Staudt LM. Lam LT, et al. Among authors: adams j. Clin Cancer Res. 2005 Jan 1;11(1):28-40. Clin Cancer Res. 2005. PMID: 15671525

2

Novel IKK inhibitors: beta-carbolines.

Castro AC, Dang LC, Soucy F, Grenier L, Mazdiyasni H, Hottelet M, Parent L, Pien C, Palombella V, Adams J. Castro AC, et al. Among authors: adams j. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2419-22. doi: 10.1016/s0960-894x(03)00408-6. Bioorg Med Chem Lett. 2003. PMID: 12824047

3

NF-kappa B as a therapeutic target in multiple myeloma.

Hideshima T, Chauhan D, Richardson P, Mitsiades C, Mitsiades N, Hayashi T, Munshi N, Dang L, Castro A, Palombella V, Adams J, Anderson KC. Hideshima T, et al. Among authors: adams j. J Biol Chem. 2002 May 10;277(19):16639-47. doi: 10.1074/jbc.M200360200. Epub 2002 Feb 28. J Biol Chem. 2002. PMID: 11872748 Free article.

4

The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents.

Ma MH, Yang HH, Parker K, Manyak S, Friedman JM, Altamirano C, Wu ZQ, Borad MJ, Frantzen M, Roussos E, Neeser J, Mikail A, Adams J, Sjak-Shie N, Vescio RA, Berenson JR. Ma MH, et al. Among authors: adams j. Clin Cancer Res. 2003 Mar;9(3):1136-44. Clin Cancer Res. 2003. PMID: 12631619

5

Mechanisms of proteasome inhibitor PS-341-induced G(2)-M-phase arrest and apoptosis in human non-small cell lung cancer cell lines.

Ling YH, Liebes L, Jiang JD, Holland JF, Elliott PJ, Adams J, Muggia FM, Perez-Soler R. Ling YH, et al. Among authors: adams j. Clin Cancer Res. 2003 Mar;9(3):1145-54. Clin Cancer Res. 2003. PMID: 12631620

6

Proteasome inhibitor PS-341 inhibits human myeloma cell growth in vivo and prolongs survival in a murine model.

LeBlanc R, Catley LP, Hideshima T, Lentzsch S, Mitsiades CS, Mitsiades N, Neuberg D, Goloubeva O, Pien CS, Adams J, Gupta D, Richardson PG, Munshi NC, Anderson KC. LeBlanc R, et al. Among authors: adams j. Cancer Res. 2002 Sep 1;62(17):4996-5000. Cancer Res. 2002. PMID: 12208752

7

Inhibition of nuclear factor-kappaB and target genes during combined therapy with proteasome inhibitor bortezomib and reirradiation in patients with recurrent head-and-neck squamous cell carcinoma.

Van Waes C, Chang AA, Lebowitz PF, Druzgal CH, Chen Z, Elsayed YA, Sunwoo JB, Rudy SF, Morris JC, Mitchell JB, Camphausen K, Gius D, Adams J, Sausville EA, Conley BA. Van Waes C, et al. Among authors: adams j. Int J Radiat Oncol Biol Phys. 2005 Dec 1;63(5):1400-12. doi: 10.1016/j.ijrobp.2005.05.007. Epub 2005 Jul 11. Int J Radiat Oncol Biol Phys. 2005. PMID: 16005577

8

Drug interactions between the proteasome inhibitor bortezomib and cytotoxic chemotherapy, tumor necrosis factor (TNF) alpha, and TNF-related apoptosis-inducing ligand in prostate cancer.

An J, Sun YP, Adams J, Fisher M, Belldegrun A, Rettig MB. An J, et al. Among authors: adams j. Clin Cancer Res. 2003 Oct 1;9(12):4537-45. Clin Cancer Res. 2003. PMID: 14555528

9

A phase I trial of the novel proteasome inhibitor PS341 in advanced solid tumor malignancies.

Aghajanian C, Soignet S, Dizon DS, Pien CS, Adams J, Elliott PJ, Sabbatini P, Miller V, Hensley ML, Pezzulli S, Canales C, Daud A, Spriggs DR. Aghajanian C, et al. Among authors: adams j. Clin Cancer Res. 2002 Aug;8(8):2505-11. Clin Cancer Res. 2002. PMID: 12171876 Clinical Trial.

10

Effects of the proteasome inhibitor PS-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts.

Nawrocki ST, Bruns CJ, Harbison MT, Bold RJ, Gotsch BS, Abbruzzese JL, Elliott P, Adams J, McConkey DJ. Nawrocki ST, et al. Among authors: adams j. Mol Cancer Ther. 2002 Dec;1(14):1243-53. Mol Cancer Ther. 2002. PMID: 12516957

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