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Periadolescent rats (P41-50) exhibit increased susceptibility to D-methamphetamine-induced long-term spatial and sequential learning deficits compared to juvenile (P21-30 or P31-40) or adult rats (P51-60).
Vorhees CV, Reed TM, Morford LL, Fukumura M, Wood SL, Brown CA, Skelton MR, McCrea AE, Rock SL, Williams MT. Vorhees CV, et al. Among authors: reed tm. Neurotoxicol Teratol. 2005 Jan-Feb;27(1):117-34. doi: 10.1016/j.ntt.2004.09.005. Neurotoxicol Teratol. 2005. PMID: 15681126
Phosphodiesterase 1B differentially modulates the effects of methamphetamine on locomotor activity and spatial learning through DARPP32-dependent pathways: evidence from PDE1B-DARPP32 double-knockout mice.
Ehrman LA, Williams MT, Schaefer TL, Gudelsky GA, Reed TM, Fienberg AA, Greengard P, Vorhees CV. Ehrman LA, et al. Among authors: reed tm. Genes Brain Behav. 2006 Oct;5(7):540-51. doi: 10.1111/j.1601-183X.2006.00209.x. Genes Brain Behav. 2006. PMID: 17010100 Free article.
31 results