Saraiva MJ - Search Results

1

Human transthyretin in complex with iododiflunisal: structural features associated with a potent amyloid inhibitor.

Gales L, Macedo-Ribeiro S, Arsequell G, Valencia G, Saraiva MJ, Damas AM. Gales L, et al. Among authors: saraiva mj. Biochem J. 2005 Jun 1;388(Pt 2):615-21. doi: 10.1042/BJ20042035. Biochem J. 2005. PMID: 15689188 Free PMC article.

2

Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivative.

Almeida MR, Macedo B, Cardoso I, Alves I, Valencia G, Arsequell G, Planas A, Saraiva MJ. Almeida MR, et al. Among authors: saraiva mj. Biochem J. 2004 Jul 15;381(Pt 2):351-6. doi: 10.1042/BJ20040011. Biochem J. 2004. PMID: 15080795 Free PMC article.

3

Deposition and passage of transthyretin through the blood-nerve barrier in recipients of familial amyloid polyneuropathy livers.

Sousa MM, Ferrão J, Fernandes R, Guimarães A, Geraldes JB, Perdigoto R, Tomé L, Mota O, Negrão L, Furtado AL, Saraiva MJ. Sousa MM, et al. Among authors: saraiva mj. Lab Invest. 2004 Jul;84(7):865-73. doi: 10.1038/labinvest.3700107. Lab Invest. 2004. PMID: 15122304 Free article.

4

In vitro inhibition of transthyretin aggregate-induced cytotoxicity by full and peptide derived forms of the soluble receptor for advanced glycation end products (RAGE).

Monteiro FA, Cardoso I, Sousa MM, Saraiva MJ. Monteiro FA, et al. Among authors: saraiva mj. FEBS Lett. 2006 Jun 12;580(14):3451-6. doi: 10.1016/j.febslet.2006.05.020. Epub 2006 May 15. FEBS Lett. 2006. PMID: 16716307 Free article.

5

Endoplasmic reticulum stress associated with extracellular aggregates. Evidence from transthyretin deposition in familial amyloid polyneuropathy.

Teixeira PF, Cerca F, Santos SD, Saraiva MJ. Teixeira PF, et al. Among authors: saraiva mj. J Biol Chem. 2006 Aug 4;281(31):21998-22003. doi: 10.1074/jbc.M602302200. Epub 2006 Jun 2. J Biol Chem. 2006. PMID: 16751191 Free article.

6

Comparative in vitro and ex vivo activities of selected inhibitors of transthyretin aggregation: relevance in drug design.

Cardoso I, Almeida MR, Ferreira N, Arsequell G, Valencia G, Saraiva MJ. Cardoso I, et al. Among authors: saraiva mj. Biochem J. 2007 Nov 15;408(1):131-8. doi: 10.1042/BJ20070689. Biochem J. 2007. PMID: 17683281 Free PMC article.

7

Iodination of salicylic acid improves its binding to transthyretin.

Gales L, Almeida MR, Arsequell G, Valencia G, Saraiva MJ, Damas AM. Gales L, et al. Among authors: saraiva mj. Biochim Biophys Acta. 2008 Mar;1784(3):512-7. doi: 10.1016/j.bbapap.2007.11.014. Epub 2007 Dec 3. Biochim Biophys Acta. 2008. PMID: 18155178

8

Anti-apoptotic treatment reduces transthyretin deposition in a transgenic mouse model of Familial Amyloidotic Polyneuropathy.

Macedo B, Batista AR, Ferreira N, Almeida MR, Saraiva MJ. Macedo B, et al. Among authors: saraiva mj. Biochim Biophys Acta. 2008 Sep;1782(9):517-22. doi: 10.1016/j.bbadis.2008.05.005. Epub 2008 Jun 3. Biochim Biophys Acta. 2008. PMID: 18572024 Free article.

9

Iodine atoms: a new molecular feature for the design of potent transthyretin fibrillogenesis inhibitors.

Mairal T, Nieto J, Pinto M, Almeida MR, Gales L, Ballesteros A, Barluenga J, Pérez JJ, Vázquez JT, Centeno NB, Saraiva MJ, Damas AM, Planas A, Arsequell G, Valencia G. Mairal T, et al. Among authors: saraiva mj. PLoS One. 2009;4(1):e4124. doi: 10.1371/journal.pone.0004124. Epub 2009 Jan 6. PLoS One. 2009. PMID: 19125186 Free PMC article.

10

Isatin derivatives, a novel class of transthyretin fibrillogenesis inhibitors.

González A, Quirante J, Nieto J, Almeida MR, Saraiva MJ, Planas A, Arsequell G, Valencia G. González A, et al. Among authors: saraiva mj. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5270-3. doi: 10.1016/j.bmcl.2009.03.004. Epub 2009 Mar 6. Bioorg Med Chem Lett. 2009. PMID: 19651509

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