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An internal domain of beta-tropomyosin increases myofilament Ca(2+) sensitivity.
Jagatheesan G, Rajan S, Schulz EM, Ahmed RP, Petrashevskaya N, Schwartz A, Boivin GP, Arteaga GM, Wang T, Wang YG, Ashraf M, Liggett SB, Lorenz J, Solaro RJ, Wieczorek DF. Jagatheesan G, et al. Among authors: boivin gp. Am J Physiol Heart Circ Physiol. 2009 Jul;297(1):H181-90. doi: 10.1152/ajpheart.00329.2008. Epub 2009 May 8. Am J Physiol Heart Circ Physiol. 2009. PMID: 19429821 Free PMC article.
Molecular and functional characterization of a novel cardiac-specific human tropomyosin isoform.
Rajan S, Jagatheesan G, Karam CN, Alves ML, Bodi I, Schwartz A, Bulcao CF, D'Souza KM, Akhter SA, Boivin GP, Dube DK, Petrashevskaya N, Herr AB, Hullin R, Liggett SB, Wolska BM, Solaro RJ, Wieczorek DF. Rajan S, et al. Among authors: boivin gp. Circulation. 2010 Jan 26;121(3):410-8. doi: 10.1161/CIRCULATIONAHA.109.889725. Epub 2010 Jan 11. Circulation. 2010. PMID: 20065163 Free PMC article.
Tropomyosin 3 expression leads to hypercontractility and attenuates myofilament length-dependent Ca(2+) activation.
Pieples K, Arteaga G, Solaro RJ, Grupp I, Lorenz JN, Boivin GP, Jagatheesan G, Labitzke E, DeTombe PP, Konhilas JP, Irving TC, Wieczorek DF. Pieples K, et al. Among authors: boivin gp. Am J Physiol Heart Circ Physiol. 2002 Oct;283(4):H1344-53. doi: 10.1152/ajpheart.00351.2002. Epub 2002 Jun 13. Am J Physiol Heart Circ Physiol. 2002. PMID: 12234784 Free article.
135 results