Castaño EM - Search Results

1

Amyloid beta degradation: a challenging task for brain peptidases.

Morelli L, Bulloj A, Leal MC, Castaño EM. Morelli L, et al. Among authors: castano em. Subcell Biochem. 2005;38:129-45. doi: 10.1007/0-387-23226-5_6. Subcell Biochem. 2005. PMID: 15709476 Review.

2

The degradation of amyloid beta as a therapeutic strategy in Alzheimer's disease and cerebrovascular amyloidoses.

Morelli L, Llovera R, Ibendahl S, Castaño EM. Morelli L, et al. Among authors: castano em. Neurochem Res. 2002 Nov;27(11):1387-99. doi: 10.1023/a:1021679817756. Neurochem Res. 2002. PMID: 12512943 Review.

3

Differential degradation of amyloid beta genetic variants associated with hereditary dementia or stroke by insulin-degrading enzyme.

Morelli L, Llovera R, Gonzalez SA, Affranchino JL, Prelli F, Frangione B, Ghiso J, Castano EM. Morelli L, et al. Among authors: castano em. J Biol Chem. 2003 Jun 27;278(26):23221-6. doi: 10.1074/jbc.M300276200. Epub 2003 Apr 14. J Biol Chem. 2003. PMID: 12695513 Free article.

4

The irreversible binding of amyloid peptide substrates to insulin-degrading enzyme: a biological perspective.

de Tullio MB, Morelli L, Castaño EM. de Tullio MB, et al. Among authors: castano em. Prion. 2008 Apr-Jun;2(2):51-6. doi: 10.4161/pri.2.2.6710. Epub 2008 May 1. Prion. 2008. PMID: 19098445 Free PMC article. Review.

5

[Cerebral proteolysis of amiloid-b peptide: relevance of insulin-degrading enzyme in Alzheimer's disease].

Leal MC, Fernandez Gamba A, Morelli L, Castaño EM. Leal MC, et al. Among authors: castano em. Medicina (B Aires). 2009;69(4):466-72. Medicina (B Aires). 2009. PMID: 19770104 Review. Spanish.

6

Insulin-degrading enzyme sorting in exosomes: a secretory pathway for a key brain amyloid-beta degrading protease.

Bulloj A, Leal MC, Xu H, Castaño EM, Morelli L. Bulloj A, et al. Among authors: castano em. J Alzheimers Dis. 2010;19(1):79-95. doi: 10.3233/JAD-2010-1206. J Alzheimers Dis. 2010. PMID: 20061628 Free PMC article.

7

Insulin-degrading enzyme in brain microvessels: proteolysis of amyloid {beta} vasculotropic variants and reduced activity in cerebral amyloid angiopathy.

Morelli L, Llovera RE, Mathov I, Lue LF, Frangione B, Ghiso J, Castaño EM. Morelli L, et al. Among authors: castano em. J Biol Chem. 2004 Dec 31;279(53):56004-13. doi: 10.1074/jbc.M407283200. Epub 2004 Oct 15. J Biol Chem. 2004. PMID: 15489232 Free article.

8

Insulin-degrading enzyme degrades amyloid peptides associated with British and Danish familial dementia.

Morelli L, Llovera RE, Alonso LG, Frangione B, de Prat-Gay G, Ghiso J, Castaño EM. Morelli L, et al. Among authors: castano em. Biochem Biophys Res Commun. 2005 Jul 8;332(3):808-16. doi: 10.1016/j.bbrc.2005.05.020. Biochem Biophys Res Commun. 2005. PMID: 15913558

9

Plaque-associated overexpression of insulin-degrading enzyme in the cerebral cortex of aged transgenic tg2576 mice with Alzheimer pathology.

Leal MC, Dorfman VB, Gamba AF, Frangione B, Wisniewski T, Castaño EM, Sigurdsson EM, Morelli L. Leal MC, et al. Among authors: castano em. J Neuropathol Exp Neurol. 2006 Oct;65(10):976-87. doi: 10.1097/01.jnen.0000235853.70092.ba. J Neuropathol Exp Neurol. 2006. PMID: 17021402

10

The catalytic domain of insulin-degrading enzyme forms a denaturant-resistant complex with amyloid beta peptide: implications for Alzheimer disease pathogenesis.

Llovera RE, de Tullio M, Alonso LG, Leissring MA, Kaufman SB, Roher AE, de Prat Gay G, Morelli L, Castaño EM. Llovera RE, et al. Among authors: castano em. J Biol Chem. 2008 Jun 20;283(25):17039-48. doi: 10.1074/jbc.M706316200. Epub 2008 Apr 14. J Biol Chem. 2008. PMID: 18411275 Free article.

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