Thinakaran G - Search Results

1

Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components.

Zhang YW, Luo WJ, Wang H, Lin P, Vetrivel KS, Liao F, Li F, Wong PC, Farquhar MG, Thinakaran G, Xu H. Zhang YW, et al. Among authors: thinakaran g. J Biol Chem. 2005 Apr 29;280(17):17020-6. doi: 10.1074/jbc.M409467200. Epub 2005 Feb 11. J Biol Chem. 2005. PMID: 15711015 Free PMC article.

2

Metabolism of the amyloid precursor-like protein 2 in MDCK cells. Polarized trafficking occurs independent of the chondroitin sulfate glycosaminoglycan chain.

Lo AC, Thinakaran G, Slunt HH, Sisodia SS. Lo AC, et al. Among authors: thinakaran g. J Biol Chem. 1995 May 26;270(21):12641-5. doi: 10.1074/jbc.270.21.12641. J Biol Chem. 1995. PMID: 7759513 Free article.

3

Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus.

Thinakaran G, Teplow DB, Siman R, Greenberg B, Sisodia SS. Thinakaran G, et al. J Biol Chem. 1996 Apr 19;271(16):9390-7. doi: 10.1074/jbc.271.16.9390. J Biol Chem. 1996. PMID: 8621605 Free article.

4

Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation.

Xu H, Sweeney D, Wang R, Thinakaran G, Lo AC, Sisodia SS, Greengard P, Gandy S. Xu H, et al. Among authors: thinakaran g. Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):3748-52. doi: 10.1073/pnas.94.8.3748. Proc Natl Acad Sci U S A. 1997. PMID: 9108049 Free PMC article.

5

Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides.

Xu H, Gouras GK, Greenfield JP, Vincent B, Naslund J, Mazzarelli L, Fried G, Jovanovic JN, Seeger M, Relkin NR, Liao F, Checler F, Buxbaum JD, Chait BT, Thinakaran G, Sisodia SS, Wang R, Greengard P, Gandy S. Xu H, et al. Among authors: thinakaran g. Nat Med. 1998 Apr;4(4):447-51. doi: 10.1038/nm0498-447. Nat Med. 1998. PMID: 9546791

6

Effects of PS1 deficiency on membrane protein trafficking in neurons.

Naruse S, Thinakaran G, Luo JJ, Kusiak JW, Tomita T, Iwatsubo T, Qian X, Ginty DD, Price DL, Borchelt DR, Wong PC, Sisodia SS. Naruse S, et al. Among authors: thinakaran g. Neuron. 1998 Nov;21(5):1213-21. doi: 10.1016/s0896-6273(00)80637-6. Neuron. 1998. PMID: 9856475 Free article.

7

Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides.

Greenfield JP, Tsai J, Gouras GK, Hai B, Thinakaran G, Checler F, Sisodia SS, Greengard P, Xu H. Greenfield JP, et al. Among authors: thinakaran g. Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):742-7. doi: 10.1073/pnas.96.2.742. Proc Natl Acad Sci U S A. 1999. PMID: 9892704 Free PMC article.

8

Lack of requirement for presenilin1 in Notch1 signaling.

Berechid BE, Thinakaran G, Wong PC, Sisodia SS, Nye JS. Berechid BE, et al. Among authors: thinakaran g. Curr Biol. 1999 Dec 16-30;9(24):1493-6. doi: 10.1016/s0960-9822(00)80121-9. Curr Biol. 1999. PMID: 10607593 Free article.

9

The nonconserved hydrophilic loop domain of presenilin (PS) is not required for PS endoproteolysis or enhanced abeta 42 production mediated by familial early onset Alzheimer's disease-linked PS variants.

Saura CA, Tomita T, Soriano S, Takahashi M, Leem JY, Honda T, Koo EH, Iwatsubo T, Thinakaran G. Saura CA, et al. Among authors: thinakaran g. J Biol Chem. 2000 Jun 2;275(22):17136-42. doi: 10.1074/jbc.M909624199. J Biol Chem. 2000. PMID: 10748144 Free article.

10

Multiple effects of aspartate mutant presenilin 1 on the processing and trafficking of amyloid precursor protein.

Kim SH, Leem JY, Lah JJ, Slunt HH, Levey AI, Thinakaran G, Sisodia SS. Kim SH, et al. Among authors: thinakaran g. J Biol Chem. 2001 Nov 16;276(46):43343-50. doi: 10.1074/jbc.M108245200. Epub 2001 Sep 19. J Biol Chem. 2001. PMID: 11564743 Free article.

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