Sacchettini JC - Search Results

1

The HPr proteins from the thermophile Bacillus stearothermophilus can form domain-swapped dimers.

Sridharan S, Razvi A, Scholtz JM, Sacchettini JC. Sridharan S, et al. Among authors: sacchettini jc. J Mol Biol. 2005 Feb 25;346(3):919-31. doi: 10.1016/j.jmb.2004.12.008. Epub 2004 Dec 23. J Mol Biol. 2005. PMID: 15713472

2

Rational design of potent human transthyretin amyloid disease inhibitors.

Klabunde T, Petrassi HM, Oza VB, Raman P, Kelly JW, Sacchettini JC. Klabunde T, et al. Among authors: sacchettini jc. Nat Struct Biol. 2000 Apr;7(4):312-21. doi: 10.1038/74082. Nat Struct Biol. 2000. PMID: 10742177

3

Reversible ligand-induced dissociation of a tryptophan-shift mutant of phosphofructokinase from Bacillus stearothermophilus.

Riley-Lovingshimer MR, Ronning DR, Sacchettini JC, Reinhart GD. Riley-Lovingshimer MR, et al. Among authors: sacchettini jc. Biochemistry. 2002 Oct 29;41(43):12967-74. doi: 10.1021/bi0263412. Biochemistry. 2002. PMID: 12390023

4

The contribution of polar group burial to protein stability is strongly context-dependent.

Takano K, Scholtz JM, Sacchettini JC, Pace CN. Takano K, et al. Among authors: sacchettini jc. J Biol Chem. 2003 Aug 22;278(34):31790-5. doi: 10.1074/jbc.M304177200. Epub 2003 Jun 10. J Biol Chem. 2003. PMID: 12799387 Free article.

5

A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.

Eicken C, Pennella MA, Chen X, Koshlap KM, VanZile ML, Sacchettini JC, Giedroc DP. Eicken C, et al. Among authors: sacchettini jc. J Mol Biol. 2003 Oct 31;333(4):683-95. doi: 10.1016/j.jmb.2003.09.007. J Mol Biol. 2003. PMID: 14568530

6

The Mycobacterium tuberculosis iniA gene is essential for activity of an efflux pump that confers drug tolerance to both isoniazid and ethambutol.

Colangeli R, Helb D, Sridharan S, Sun J, Varma-Basil M, Hazbón MH, Harbacheuski R, Megjugorac NJ, Jacobs WR Jr, Holzenburg A, Sacchettini JC, Alland D. Colangeli R, et al. Among authors: sacchettini jc. Mol Microbiol. 2005 Mar;55(6):1829-40. doi: 10.1111/j.1365-2958.2005.04510.x. Mol Microbiol. 2005. PMID: 15752203 Free article.

7

Probing the mechanism of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III mtFabH: factors influencing catalysis and substrate specificity.

Brown AK, Sridharan S, Kremer L, Lindenberg S, Dover LG, Sacchettini JC, Besra GS. Brown AK, et al. Among authors: sacchettini jc. J Biol Chem. 2005 Sep 16;280(37):32539-47. doi: 10.1074/jbc.M413216200. Epub 2005 Jul 22. J Biol Chem. 2005. PMID: 16040614 Free article.

8

Asp79 makes a large, unfavorable contribution to the stability of RNase Sa.

Trevino SR, Gokulan K, Newsom S, Thurlkill RL, Shaw KL, Mitkevich VA, Makarov AA, Sacchettini JC, Scholtz JM, Pace CN. Trevino SR, et al. Among authors: sacchettini jc. J Mol Biol. 2005 Dec 9;354(4):967-78. doi: 10.1016/j.jmb.2005.09.091. Epub 2005 Oct 21. J Mol Biol. 2005. PMID: 16288913

9

X-ray crystal structure of Mycobacterium tuberculosis beta-ketoacyl acyl carrier protein synthase II (mtKasB).

Sridharan S, Wang L, Brown AK, Dover LG, Kremer L, Besra GS, Sacchettini JC. Sridharan S, et al. Among authors: sacchettini jc. J Mol Biol. 2007 Feb 16;366(2):469-80. doi: 10.1016/j.jmb.2006.11.006. Epub 2006 Nov 7. J Mol Biol. 2007. PMID: 17174327 Free PMC article.

10

Structural insight into pH-induced conformational changes within the native human transthyretin tetramer.

Palaninathan SK, Mohamedmohaideen NN, Snee WC, Kelly JW, Sacchettini JC. Palaninathan SK, et al. Among authors: sacchettini jc. J Mol Biol. 2008 Oct 24;382(5):1157-67. doi: 10.1016/j.jmb.2008.07.029. Epub 2008 Jul 16. J Mol Biol. 2008. PMID: 18662699

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