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SHP2 Inhibition Overcomes RTK-Mediated Pathway Reactivation in KRAS-Mutant Tumors Treated with MEK Inhibitors.
Lu H, Liu C, Velazquez R, Wang H, Dunkl LM, Kazic-Legueux M, Haberkorn A, Billy E, Manchado E, Brachmann SM, Moody SE, Engelman JA, Hammerman PS, Caponigro G, Mohseni M, Hao HX. Lu H, et al. Among authors: brachmann sm. Mol Cancer Ther. 2019 Jul;18(7):1323-1334. doi: 10.1158/1535-7163.MCT-18-0852. Epub 2019 May 8. Mol Cancer Ther. 2019. PMID: 31068384
p85 Associates with unphosphorylated PTEN and the PTEN-associated complex.
Rabinovsky R, Pochanard P, McNear C, Brachmann SM, Duke-Cohan JS, Garraway LA, Sellers WR. Rabinovsky R, et al. Among authors: brachmann sm. Mol Cell Biol. 2009 Oct;29(19):5377-88. doi: 10.1128/MCB.01649-08. Epub 2009 Jul 27. Mol Cell Biol. 2009. PMID: 19635806 Free PMC article.
Dual regulatory roles of phosphatidylinositol 3-kinase in IFN signaling.
Kaur S, Sassano A, Joseph AM, Majchrzak-Kita B, Eklund EA, Verma A, Brachmann SM, Fish EN, Platanias LC. Kaur S, et al. Among authors: brachmann sm. J Immunol. 2008 Nov 15;181(10):7316-23. doi: 10.4049/jimmunol.181.10.7316. J Immunol. 2008. PMID: 18981154 Free PMC article.
35 results