Ley JJ - Search Results

1

Stilbazulenyl nitrone, a second-generation azulenyl nitrone antioxidant, confers enduring neuroprotection in experimental focal cerebral ischemia in the rat: neurobehavior, histopathology, and pharmacokinetics.

Ley JJ, Vigdorchik A, Belayev L, Zhao W, Busto R, Khoutorova L, Becker DA, Ginsberg MD. Ley JJ, et al. J Pharmacol Exp Ther. 2005 Jun;313(3):1090-100. doi: 10.1124/jpet.105.083386. Epub 2005 Feb 16. J Pharmacol Exp Ther. 2005. PMID: 15716383

2

Stilbazulenyl nitrone, a novel azulenyl nitrone antioxidant: improved neurological deficit and reduced contusion size after traumatic brain injury in rats.

Belayev L, Becker DA, Alonso OF, Liu Y, Busto R, Ley JJ, Ginsberg MD. Belayev L, et al. Among authors: ley jj. J Neurosurg. 2002 Jun;96(6):1077-83. doi: 10.3171/jns.2002.96.6.1077. J Neurosurg. 2002. PMID: 12066910

3

Stilbazulenyl nitrone, a novel antioxidant, is highly neuroprotective in focal ischemia.

Ginsberg MD, Becker DA, Busto R, Belayev A, Zhang Y, Khoutorova L, Ley JJ, Zhao W, Belayev L. Ginsberg MD, et al. Among authors: ley jj. Ann Neurol. 2003 Sep;54(3):330-42. doi: 10.1002/ana.10659. Ann Neurol. 2003. PMID: 12953265

4

A novel azulenyl nitrone antioxidant protects against MPTP and 3-nitropropionic acid neurotoxicities.

Yang L, Calingasan NY, Chen J, Ley JJ, Becker DA, Beal MF. Yang L, et al. Among authors: ley jj. Exp Neurol. 2005 Jan;191(1):86-93. doi: 10.1016/j.expneurol.2004.07.012. Exp Neurol. 2005. PMID: 15589515

5

Neuroprotective antioxidant STAZN protects against myocardial ischemia/reperfusion injury.

Ley JJ, Prado R, Wei JQ, Bishopric NH, Becker DA, Ginsberg MD. Ley JJ, et al. Biochem Pharmacol. 2008 Jan 15;75(2):448-56. doi: 10.1016/j.bcp.2007.09.001. Epub 2007 Sep 8. Biochem Pharmacol. 2008. PMID: 17936251 Free PMC article.

6

Neuroprotective effect of STAZN, a novel azulenyl nitrone antioxidant, in focal cerebral ischemia in rats: dose-response and therapeutic window.

Ley JJ, Belayev L, Saul I, Becker DA, Ginsberg MD. Ley JJ, et al. Brain Res. 2007 Nov 14;1180:101-10. doi: 10.1016/j.brainres.2007.05.028. Epub 2007 May 26. Brain Res. 2007. PMID: 17945201 Free PMC article.

7

Stilbazulenyl nitrone (STAZN): a nitronyl-substituted hydrocarbon with the potency of classical phenolic chain-breaking antioxidants.

Becker DA, Ley JJ, Echegoyen L, Alvarado R. Becker DA, et al. Among authors: ley jj. J Am Chem Soc. 2002 May 1;124(17):4678-84. doi: 10.1021/ja011507s. J Am Chem Soc. 2002. PMID: 11971716

8

Kinetic studies on stilbazulenyl-bis-nitrone (STAZN), a nonphenolic chain-breaking antioxidant in solution, micelles, and lipid membranes.

Mojumdar SC, Becker DA, DiLabio GA, Ley JJ, Barclay LR, Ingold KU. Mojumdar SC, et al. Among authors: ley jj. J Org Chem. 2004 Apr 30;69(9):2929-36. doi: 10.1021/jo030390i. J Org Chem. 2004. PMID: 15104428

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