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Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder.
Abdolmaleky HM, Cheng KH, Faraone SV, Wilcox M, Glatt SJ, Gao F, Smith CL, Shafa R, Aeali B, Carnevale J, Pan H, Papageorgis P, Ponte JF, Sivaraman V, Tsuang MT, Thiagalingam S. Abdolmaleky HM, et al. Among authors: shafa r. Hum Mol Genet. 2006 Nov 1;15(21):3132-45. doi: 10.1093/hmg/ddl253. Epub 2006 Sep 19. Hum Mol Genet. 2006. PMID: 16984965 Free PMC article.
Aberrant transcriptomes and DNA methylomes define pathways that drive pathogenesis and loss of brain laterality/asymmetry in schizophrenia and bipolar disorder.
Abdolmaleky HM, Gower AC, Wong CK, Cox JW, Zhang X, Thiagalingam A, Shafa R, Sivaraman V, Zhou JR, Thiagalingam S. Abdolmaleky HM, et al. Among authors: shafa r. Am J Med Genet B Neuropsychiatr Genet. 2019 Mar;180(2):138-149. doi: 10.1002/ajmg.b.32691. Epub 2018 Nov 23. Am J Med Genet B Neuropsychiatr Genet. 2019. PMID: 30468562 Free PMC article.