Brookes AJ - Search Results

1

Sequence variants of IDE are associated with the extent of beta-amyloid deposition in the Alzheimer's disease brain.

Blomqvist ME, Chalmers K, Andreasen N, Bogdanovic N, Wilcock GK, Cairns NJ, Feuk L, Brookes AJ, Love S, Blennow K, Kehoe PG, Prince JA. Blomqvist ME, et al. Among authors: brookes aj. Neurobiol Aging. 2005 Jun;26(6):795-802. doi: 10.1016/j.neurobiolaging.2004.07.011. Neurobiol Aging. 2005. PMID: 15718037 Clinical Trial.

2

Identification of 167 polymorphisms in 88 genes from candidate neurodegeneration pathways.

Emahazion T, Jobs M, Howell WM, Siegfried M, Wyöni PI, Prince JA, Brookes AJ. Emahazion T, et al. Among authors: brookes aj. Gene. 1999 Oct 1;238(2):315-24. doi: 10.1016/s0378-1119(99)00330-3. Gene. 1999. PMID: 10570959

3

No association between the alpha2-macroglobulin (A2M) deletion and Alzheimer's disease, and no change in A2M mRNA, protein, or protein expression.

Blennow K, Ricksten A, Prince JA, Brookes AJ, Emahazion T, Wasslavik C, Bogdanovic N, Andreasen N, Båtsman S, Marcusson J, Nägga K, Wallin A, Regland B, Olofsson H, Hesse C, Davidsson P, Minthon L, Jansson A, Palmqvist L, Rymo L. Blennow K, et al. Among authors: brookes aj. J Neural Transm (Vienna). 2000;107(8-9):1065-79. doi: 10.1007/s007020070052. J Neural Transm (Vienna). 2000. PMID: 11041282

4

apolipoprotein-E dependent role for the FAS receptor in early onset Alzheimer's disease: finding of a positive association for a polymorphism in the TNFRSF6 gene.

Feuk L, Prince JA, Breen G, Emahazion T, Carothers A, St Clair D, Brookes AJ. Feuk L, et al. Among authors: brookes aj. Hum Genet. 2000 Oct;107(4):391-6. doi: 10.1007/s004390000383. Hum Genet. 2000. PMID: 11129341

5

Robust and accurate single nucleotide polymorphism genotyping by dynamic allele-specific hybridization (DASH): design criteria and assay validation.

Prince JA, Feuk L, Howell WM, Jobs M, Emahazion T, Blennow K, Brookes AJ. Prince JA, et al. Among authors: brookes aj. Genome Res. 2001 Jan;11(1):152-62. doi: 10.1101/gr.150201. Genome Res. 2001. PMID: 11156624 Free PMC article.

6

SNP association studies in Alzheimer's disease highlight problems for complex disease analysis.

Emahazion T, Feuk L, Jobs M, Sawyer SL, Fredman D, St Clair D, Prince JA, Brookes AJ. Emahazion T, et al. Among authors: brookes aj. Trends Genet. 2001 Jul;17(7):407-13. doi: 10.1016/s0168-9525(01)02342-3. Trends Genet. 2001. PMID: 11418222 Review.

7

Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease.

Prince JA, Feuk L, Sawyer SL, Gottfries J, Ricksten A, Nägga K, Bogdanovic N, Blennow K, Brookes AJ. Prince JA, et al. Among authors: brookes aj. Eur J Hum Genet. 2001 Jun;9(6):437-44. doi: 10.1038/sj.ejhg.5200651. Eur J Hum Genet. 2001. PMID: 11436125

8

Towards high-throughput genotyping of SNPs by dynamic allele-specific hybridization.

Prince JA, Brookes AJ. Prince JA, et al. Among authors: brookes aj. Expert Rev Mol Diagn. 2001 Sep;1(3):352-8. doi: 10.1586/14737159.1.3.352. Expert Rev Mol Diagn. 2001. PMID: 11901841

9

Evaluation of multiple presenilin 2 SNPs for association with early-onset sporadic Alzheimer disease.

Howell WM, Brookes AJ. Howell WM, et al. Among authors: brookes aj. Am J Med Genet. 2002 Aug 1;111(2):157-63. doi: 10.1002/ajmg.10533. Am J Med Genet. 2002. PMID: 12210343

10

Further evidence for role of a promoter variant in the TNFRSF6 gene in Alzheimer disease.

Feuk L, Prince JA, Blennow K, Brookes AJ. Feuk L, et al. Among authors: brookes aj. Hum Mutat. 2003 Jan;21(1):53-60. doi: 10.1002/humu.10148. Hum Mutat. 2003. PMID: 12497631

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