Lang T - Search Results

1

A natural CYP2B6 TATA box polymorphism (-82T--> C) leading to enhanced transcription and relocation of the transcriptional start site.

Zukunft J, Lang T, Richter T, Hirsch-Ernst KI, Nussler AK, Klein K, Schwab M, Eichelbaum M, Zanger UM. Zukunft J, et al. Among authors: lang t. Mol Pharmacol. 2005 May;67(5):1772-82. doi: 10.1124/mol.104.008086. Epub 2005 Feb 18. Mol Pharmacol. 2005. PMID: 15722458

2

The influence of CYP2B6, CYP2C9 and CYP2D6 genotypes on the formation of the potent antioestrogen Z-4-hydroxy-tamoxifen in human liver.

Coller JK, Krebsfaenger N, Klein K, Endrizzi K, Wolbold R, Lang T, Nüssler A, Neuhaus P, Zanger UM, Eichelbaum M, Mürdter TE. Coller JK, et al. Among authors: lang t. Br J Clin Pharmacol. 2002 Aug;54(2):157-67. doi: 10.1046/j.1365-2125.2002.01614.x. Br J Clin Pharmacol. 2002. PMID: 12207635 Free PMC article.

3

Detection of single nucleotide polymorphisms in CYP2B6 gene.

Zanger UM, Fischer J, Klein K, Lang T. Zanger UM, et al. Among authors: lang t. Methods Enzymol. 2002;357:45-53. doi: 10.1016/s0076-6879(02)57664-3. Methods Enzymol. 2002. PMID: 12424896 No abstract available.

4

Multiple novel nonsynonymous CYP2B6 gene polymorphisms in Caucasians: demonstration of phenotypic null alleles.

Lang T, Klein K, Richter T, Zibat A, Kerb R, Eichelbaum M, Schwab M, Zanger UM. Lang T, et al. J Pharmacol Exp Ther. 2004 Oct;311(1):34-43. doi: 10.1124/jpet.104.068973. Epub 2004 Jun 9. J Pharmacol Exp Ther. 2004. PMID: 15190123

5

Genetic variability of CYP2B6 in populations of African and Asian origin: allele frequencies, novel functional variants, and possible implications for anti-HIV therapy with efavirenz.

Klein K, Lang T, Saussele T, Barbosa-Sicard E, Schunck WH, Eichelbaum M, Schwab M, Zanger UM. Klein K, et al. Among authors: lang t. Pharmacogenet Genomics. 2005 Dec;15(12):861-73. doi: 10.1097/01213011-200512000-00004. Pharmacogenet Genomics. 2005. PMID: 16272958

6

Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver.

Lang T, Klein K, Fischer J, Nüssler AK, Neuhaus P, Hofmann U, Eichelbaum M, Schwab M, Zanger UM. Lang T, et al. Pharmacogenetics. 2001 Jul;11(5):399-415. doi: 10.1097/00008571-200107000-00004. Pharmacogenetics. 2001. PMID: 11470993

7

High-throughput genotyping of thiopurine S-methyltransferase by denaturing HPLC.

Schaeffeler E, Lang T, Zanger UM, Eichelbaum M, Schwab M. Schaeffeler E, et al. Among authors: lang t. Clin Chem. 2001 Mar;47(3):548-55. Clin Chem. 2001. PMID: 11238310

8

ABCC11/MRP8 polymorphisms affect 5-fluorouracil-induced severe toxicity and hepatic expression.

Magdy T, Arlanov R, Winter S, Lang T, Klein K, Toyoda Y, Ishikawa T, Schwab M, Zanger UM. Magdy T, et al. Among authors: lang t. Pharmacogenomics. 2013 Sep;14(12):1433-48. doi: 10.2217/pgs.13.139. Pharmacogenomics. 2013. PMID: 24024896

9

Azathioprine therapy and adverse drug reactions in patients with inflammatory bowel disease: impact of thiopurine S-methyltransferase polymorphism.

Schwab M, Schäffeler E, Marx C, Fischer C, Lang T, Behrens C, Gregor M, Eichelbaum M, Zanger UM, Kaskas BA. Schwab M, et al. Among authors: lang t. Pharmacogenetics. 2002 Aug;12(6):429-36. doi: 10.1097/00008571-200208000-00003. Pharmacogenetics. 2002. PMID: 12172211

10

High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1).

Niemi M, Schaeffeler E, Lang T, Fromm MF, Neuvonen M, Kyrklund C, Backman JT, Kerb R, Schwab M, Neuvonen PJ, Eichelbaum M, Kivistö KT. Niemi M, et al. Among authors: lang t. Pharmacogenetics. 2004 Jul;14(7):429-40. doi: 10.1097/01.fpc.0000114750.08559.32. Pharmacogenetics. 2004. PMID: 15226675

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