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1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-HT1A, 5-HT2A, 5-HT7), alpha1-adrenergic, and dopaminergic D2 receptors, and in vivo 5-HT1A functional characteristics.
Bojarski AJ, Paluchowska MH, Duszyńska B, Kłodzińska A, Tatarczyńska E, Chojnacka-Wójcik E. Bojarski AJ, et al. Bioorg Med Chem. 2005 Mar 15;13(6):2293-303. doi: 10.1016/j.bmc.2004.12.041. Bioorg Med Chem. 2005. PMID: 15727878
Synthesis and pharmacological evaluation of new arylpiperazines. 3-[4-[4-(3-chlorophenyl)-1-piperazinyl]butyl]-quinazolidin-4-one - a dual serotonin 5-HT(1A)/5-HT(2A) receptor ligand with an anxiolytic-like activity.
Bojarski AJ, Kowalski P, Kowalska T, Duszyńska B, Charakchieva-Minol S, Tatarczyńska E, Kłodzińska A, Chojnacka-Wójcik E. Bojarski AJ, et al. Bioorg Med Chem. 2002 Dec;10(12):3817-27. doi: 10.1016/s0968-0896(02)00349-8. Bioorg Med Chem. 2002. PMID: 12413835
150 results