Deak M - Search Results

1

Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate.

Jaleel M, McBride A, Lizcano JM, Deak M, Toth R, Morrice NA, Alessi DR. Jaleel M, et al. Among authors: deak m. FEBS Lett. 2005 Feb 28;579(6):1417-23. doi: 10.1016/j.febslet.2005.01.042. FEBS Lett. 2005. PMID: 15733851 Free article.

2

Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome.

Sapkota GP, Boudeau J, Deak M, Kieloch A, Morrice N, Alessi DR. Sapkota GP, et al. Among authors: deak m. Biochem J. 2002 Mar 1;362(Pt 2):481-90. doi: 10.1042/0264-6021:3620481. Biochem J. 2002. PMID: 11853558 Free PMC article.

3

Molecular basis for the substrate specificity of NIMA-related kinase-6 (NEK6). Evidence that NEK6 does not phosphorylate the hydrophobic motif of ribosomal S6 protein kinase and serum- and glucocorticoid-induced protein kinase in vivo.

Lizcano JM, Deak M, Morrice N, Kieloch A, Hastie CJ, Dong L, Schutkowski M, Reimer U, Alessi DR. Lizcano JM, et al. Among authors: deak m. J Biol Chem. 2002 Aug 2;277(31):27839-49. doi: 10.1074/jbc.M202042200. Epub 2002 May 22. J Biol Chem. 2002. PMID: 12023960 Free article.

4

Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366.

Sapkota GP, Deak M, Kieloch A, Morrice N, Goodarzi AA, Smythe C, Shiloh Y, Lees-Miller SP, Alessi DR. Sapkota GP, et al. Among authors: deak m. Biochem J. 2002 Dec 1;368(Pt 2):507-16. doi: 10.1042/BJ20021284. Biochem J. 2002. PMID: 12234250 Free PMC article.

5

Heat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stability.

Boudeau J, Deak M, Lawlor MA, Morrice NA, Alessi DR. Boudeau J, et al. Among authors: deak m. Biochem J. 2003 Mar 15;370(Pt 3):849-57. doi: 10.1042/BJ20021813. Biochem J. 2003. PMID: 12489981 Free PMC article.

6

MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm.

Boudeau J, Baas AF, Deak M, Morrice NA, Kieloch A, Schutkowski M, Prescott AR, Clevers HC, Alessi DR. Boudeau J, et al. Among authors: deak m. EMBO J. 2003 Oct 1;22(19):5102-14. doi: 10.1093/emboj/cdg490. EMBO J. 2003. PMID: 14517248 Free PMC article.

7

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.

Lizcano JM, Göransson O, Toth R, Deak M, Morrice NA, Boudeau J, Hawley SA, Udd L, Mäkelä TP, Hardie DG, Alessi DR. Lizcano JM, et al. Among authors: deak m. EMBO J. 2004 Feb 25;23(4):833-43. doi: 10.1038/sj.emboj.7600110. Epub 2004 Feb 19. EMBO J. 2004. PMID: 14976552 Free PMC article.

8

The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases.

Vitari AC, Deak M, Morrice NA, Alessi DR. Vitari AC, et al. Among authors: deak m. Biochem J. 2005 Oct 1;391(Pt 1):17-24. doi: 10.1042/BJ20051180. Biochem J. 2005. PMID: 16083423 Free PMC article.

9

14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK.

Al-Hakim AK, Göransson O, Deak M, Toth R, Campbell DG, Morrice NA, Prescott AR, Alessi DR. Al-Hakim AK, et al. Among authors: deak m. J Cell Sci. 2005 Dec 1;118(Pt 23):5661-73. doi: 10.1242/jcs.02670. J Cell Sci. 2005. PMID: 16306228

10

The ubiquitin-associated domain of AMPK-related kinases regulates conformation and LKB1-mediated phosphorylation and activation.

Jaleel M, Villa F, Deak M, Toth R, Prescott AR, Van Aalten DM, Alessi DR. Jaleel M, et al. Among authors: deak m. Biochem J. 2006 Mar 15;394(Pt 3):545-55. doi: 10.1042/BJ20051844. Biochem J. 2006. PMID: 16396636 Free PMC article.

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