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Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils.
Condliffe AM, Davidson K, Anderson KE, Ellson CD, Crabbe T, Okkenhaug K, Vanhaesebroeck B, Turner M, Webb L, Wymann MP, Hirsch E, Ruckle T, Camps M, Rommel C, Jackson SP, Chilvers ER, Stephens LR, Hawkins PT. Condliffe AM, et al. Among authors: hirsch e. Blood. 2005 Aug 15;106(4):1432-40. doi: 10.1182/blood-2005-03-0944. Epub 2005 May 5. Blood. 2005. PMID: 15878979 Free article.
Phosphoinositide 3-kinase gamma: a key modulator in inflammation and allergy.
Wymann MP, Björklöf K, Calvez R, Finan P, Thomast M, Trifilieff A, Barbier M, Altruda F, Hirsch E, Laffargue M. Wymann MP, et al. Among authors: hirsch e. Biochem Soc Trans. 2003 Feb;31(Pt 1):275-80. doi: 10.1042/bst0310275. Biochem Soc Trans. 2003. PMID: 12546701 Review.
PI(3)Kgamma has an important context-dependent role in neutrophil chemokinesis.
Ferguson GJ, Milne L, Kulkarni S, Sasaki T, Walker S, Andrews S, Crabbe T, Finan P, Jones G, Jackson S, Camps M, Rommel C, Wymann M, Hirsch E, Hawkins P, Stephens L. Ferguson GJ, et al. Among authors: hirsch e. Nat Cell Biol. 2007 Jan;9(1):86-91. doi: 10.1038/ncb1517. Epub 2006 Dec 17. Nat Cell Biol. 2007. PMID: 17173040
1,571 results