Powell WS - Search Results

1

iPF2alpha-III-17,18,19,20-d4: total synthesis and metabolism.

Kim S, Powell WS, Lawson JA, Jacobo SH, Pratico D, FitzGerald GA, Maxey K, Rokach J. Kim S, et al. Among authors: powell ws. Bioorg Med Chem Lett. 2005 Mar 15;15(6):1613-7. doi: 10.1016/j.bmcl.2005.01.062. Bioorg Med Chem Lett. 2005. PMID: 15745808

2

Total synthesis of isoprostanes: discovery and quantitation in biological systems.

Rokach J, Kim S, Bellone S, Lawson JA, Praticò D, Powell WS, FitzGerald GA. Rokach J, et al. Among authors: powell ws. Chem Phys Lipids. 2004 Mar;128(1-2):35-56. doi: 10.1016/j.chemphyslip.2003.09.011. Chem Phys Lipids. 2004. PMID: 15037151 Review.

3

Synthesis of 15R-PGD2: a potential DP2 receptor agonist.

Kim S, Bellone S, Maxey KM, Powell WS, Lee GJ, Rokach J. Kim S, et al. Among authors: powell ws. Bioorg Med Chem Lett. 2005 Apr 1;15(7):1873-6. doi: 10.1016/j.bmcl.2005.02.011. Bioorg Med Chem Lett. 2005. PMID: 15780624

4

Total synthesis of 8,12-iso-iPF3alpha-VI, an EPA-derived isoprostane: stereoselective introduction of the fifth asymmetric center.

Jacobo SH, Chang CT, Lee GJ, Lawson JA, Powell WS, Pratico D, FitzGerald GA, Rokach J. Jacobo SH, et al. Among authors: powell ws. J Org Chem. 2006 Feb 17;71(4):1370-9. doi: 10.1021/jo051916x. J Org Chem. 2006. PMID: 16468784

5

Eicosapentaenoic-acid-derived isoprostanes: synthesis and discovery of two major isoprostanes.

Chang CT, Patel P, Kang N, Lawson JA, Song WL, Powell WS, FitzGerald GA, Rokach J. Chang CT, et al. Among authors: powell ws. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5523-7. doi: 10.1016/j.bmcl.2008.09.008. Epub 2008 Sep 6. Bioorg Med Chem Lett. 2008. PMID: 18804370 Free PMC article.

6

A new approach to the synthesis of polyunsaturated deuterated isoprostanes: total synthesis of d4-5-epi-8,12-iso-iPF3alpha-VI and d4-8,12-iso-iPF3alpha-VI.

Chang CT, Patel P, Gore V, Song WL, Lawson JA, Powell WS, Fitzgerald GA, Rokach J. Chang CT, et al. Among authors: powell ws. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6755-8. doi: 10.1016/j.bmcl.2009.09.099. Epub 2009 Sep 29. Bioorg Med Chem Lett. 2009. PMID: 19846297 Free PMC article.

7

5-oxo-15-HETE: total synthesis and bioactivity.

Patel P, Anumolu JR, Powell WS, Rokach J. Patel P, et al. Among authors: powell ws. Bioorg Med Chem Lett. 2011 Mar 15;21(6):1857-60. doi: 10.1016/j.bmcl.2011.01.032. Epub 2011 Jan 25. Bioorg Med Chem Lett. 2011. PMID: 21316960 Free PMC article.

8

C20-trifluoro-5-oxo-ETE: a metabolically stable 5-oxo-ETE derivative.

Patel P, Gore V, Powell WS, Rokach J. Patel P, et al. Among authors: powell ws. Bioorg Med Chem Lett. 2011 Apr 1;21(7):1987-90. doi: 10.1016/j.bmcl.2011.02.021. Epub 2011 Feb 12. Bioorg Med Chem Lett. 2011. PMID: 21377873 Free PMC article.

9

Synthesis of 10,11-Dihydro-12-oxo-LTB(4), a Key Biochemical Intermediate.

Khanapure SP, Wang SS, Powell WS, Rokach J. Khanapure SP, et al. Among authors: powell ws. J Org Chem. 1997 Jan 24;62(2):325-330. doi: 10.1021/jo9614957. J Org Chem. 1997. PMID: 11671406

10

Base-dependent formation of cis and trans olefins and their application in the synthesis of 5-oxo-ETE receptor antagonists.

Gore V, Chourey S, Ye Q, Patel P, Ouedraogo Y, Gravel S, Powell WS, Rokach J. Gore V, et al. Among authors: powell ws. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3385-8. doi: 10.1016/j.bmcl.2014.05.090. Epub 2014 Jun 4. Bioorg Med Chem Lett. 2014. PMID: 24948567

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