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The Apc 1322T mouse develops severe polyposis associated with submaximal nuclear beta-catenin expression.
Pollard P, Deheragoda M, Segditsas S, Lewis A, Rowan A, Howarth K, Willis L, Nye E, McCart A, Mandir N, Silver A, Goodlad R, Stamp G, Cockman M, East P, Spencer-Dene B, Poulsom R, Wright N, Tomlinson I. Pollard P, et al. Gastroenterology. 2009 Jun;136(7):2204-2213.e1-13. doi: 10.1053/j.gastro.2009.02.058. Epub 2009 Feb 25. Gastroenterology. 2009. PMID: 19248780
Adult leydig cell tumors of the testis caused by germline fumarate hydratase mutations.
Carvajal-Carmona LG, Alam NA, Pollard PJ, Jones AM, Barclay E, Wortham N, Pignatelli M, Freeman A, Pomplun S, Ellis I, Poulsom R, El-Bahrawy MA, Berney DM, Tomlinson IP. Carvajal-Carmona LG, et al. Among authors: pollard pj. J Clin Endocrinol Metab. 2006 Aug;91(8):3071-5. doi: 10.1210/jc.2006-0183. Epub 2006 Jun 6. J Clin Endocrinol Metab. 2006. PMID: 16757530
SDH mutations in cancer.
Bardella C, Pollard PJ, Tomlinson I. Bardella C, et al. Biochim Biophys Acta. 2011 Nov;1807(11):1432-43. doi: 10.1016/j.bbabio.2011.07.003. Epub 2011 Jul 13. Biochim Biophys Acta. 2011. PMID: 21771581 Free article. Review.
Expression of HIF-1alpha, HIF-2alpha (EPAS1), and their target genes in paraganglioma and pheochromocytoma with VHL and SDH mutations.
Pollard PJ, El-Bahrawy M, Poulsom R, Elia G, Killick P, Kelly G, Hunt T, Jeffery R, Seedhar P, Barwell J, Latif F, Gleeson MJ, Hodgson SV, Stamp GW, Tomlinson IP, Maher ER. Pollard PJ, et al. J Clin Endocrinol Metab. 2006 Nov;91(11):4593-8. doi: 10.1210/jc.2006-0920. Epub 2006 Sep 5. J Clin Endocrinol Metab. 2006. PMID: 16954163
Genetic and functional analyses of FH mutations in multiple cutaneous and uterine leiomyomatosis, hereditary leiomyomatosis and renal cancer, and fumarate hydratase deficiency.
Alam NA, Rowan AJ, Wortham NC, Pollard PJ, Mitchell M, Tyrer JP, Barclay E, Calonje E, Manek S, Adams SJ, Bowers PW, Burrows NP, Charles-Holmes R, Cook LJ, Daly BM, Ford GP, Fuller LC, Hadfield-Jones SE, Hardwick N, Highet AS, Keefe M, MacDonald-Hull SP, Potts ED, Crone M, Wilkinson S, Camacho-Martinez F, Jablonska S, Ratnavel R, MacDonald A, Mann RJ, Grice K, Guillet G, Lewis-Jones MS, McGrath H, Seukeran DC, Morrison PJ, Fleming S, Rahman S, Kelsell D, Leigh I, Olpin S, Tomlinson IP. Alam NA, et al. Among authors: pollard pj. Hum Mol Genet. 2003 Jun 1;12(11):1241-52. doi: 10.1093/hmg/ddg148. Hum Mol Genet. 2003. PMID: 12761039
Rare insights into cancer biology.
Adam J, Yang M, Soga T, Pollard PJ. Adam J, et al. Among authors: pollard pj. Oncogene. 2014 May 15;33(20):2547-56. doi: 10.1038/onc.2013.222. Epub 2013 Jul 1. Oncogene. 2014. PMID: 23812428 Review.
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
Frezza C, Zheng L, Folger O, Rajagopalan KN, MacKenzie ED, Jerby L, Micaroni M, Chaneton B, Adam J, Hedley A, Kalna G, Tomlinson IP, Pollard PJ, Watson DG, Deberardinis RJ, Shlomi T, Ruppin E, Gottlieb E. Frezza C, et al. Among authors: pollard pj. Nature. 2011 Aug 17;477(7363):225-8. doi: 10.1038/nature10363. Nature. 2011. PMID: 21849978
118 results