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The Mycobacterium tuberculosis iniA gene is essential for activity of an efflux pump that confers drug tolerance to both isoniazid and ethambutol.
Colangeli R, Helb D, Sridharan S, Sun J, Varma-Basil M, Hazbón MH, Harbacheuski R, Megjugorac NJ, Jacobs WR Jr, Holzenburg A, Sacchettini JC, Alland D. Colangeli R, et al. Among authors: hazbon mh. Mol Microbiol. 2005 Mar;55(6):1829-40. doi: 10.1111/j.1365-2958.2005.04510.x. Mol Microbiol. 2005. PMID: 15752203 Free article.
Rapid detection of rifampin resistance in Mycobacterium tuberculosis isolates from India and Mexico by a molecular beacon assay.
Varma-Basil M, El-Hajj H, Colangeli R, Hazbón MH, Kumar S, Bose M, Bobadilla-del-Valle M, García LG, Hernández A, Kramer FR, Osornio JS, Ponce-de-León A, Alland D. Varma-Basil M, et al. Among authors: hazbon mh. J Clin Microbiol. 2004 Dec;42(12):5512-6. doi: 10.1128/JCM.42.12.5512-5516.2004. J Clin Microbiol. 2004. PMID: 15583274 Free PMC article.
Role of embB codon 306 mutations in Mycobacterium tuberculosis revisited: a novel association with broad drug resistance and IS6110 clustering rather than ethambutol resistance.
Hazbón MH, Bobadilla del Valle M, Guerrero MI, Varma-Basil M, Filliol I, Cavatore M, Colangeli R, Safi H, Billman-Jacobe H, Lavender C, Fyfe J, García-García L, Davidow A, Brimacombe M, León CI, Porras T, Bose M, Chaves F, Eisenach KD, Sifuentes-Osornio J, Ponce de León A, Cave MD, Alland D. Hazbón MH, et al. Antimicrob Agents Chemother. 2005 Sep;49(9):3794-802. doi: 10.1128/AAC.49.9.3794-3802.2005. Antimicrob Agents Chemother. 2005. PMID: 16127055 Free PMC article.
Population genetics study of isoniazid resistance mutations and evolution of multidrug-resistant Mycobacterium tuberculosis.
Hazbón MH, Brimacombe M, Bobadilla del Valle M, Cavatore M, Guerrero MI, Varma-Basil M, Billman-Jacobe H, Lavender C, Fyfe J, García-García L, León CI, Bose M, Chaves F, Murray M, Eisenach KD, Sifuentes-Osornio J, Cave MD, Ponce de León A, Alland D. Hazbón MH, et al. Antimicrob Agents Chemother. 2006 Aug;50(8):2640-9. doi: 10.1128/AAC.00112-06. Antimicrob Agents Chemother. 2006. PMID: 16870753 Free PMC article.
34 results