Holý A - Search Results

1

Synthesis and immunobiological activity of base substituted 2-amino-3-(purin-9-yl)propanoic acid derivatives.

Doláková P, Holý A, Zídek Z, Masojídková M, Kmonícková E. Doláková P, et al. Among authors: holy a. Bioorg Med Chem. 2005 Apr 1;13(7):2349-54. doi: 10.1016/j.bmc.2005.01.054. Bioorg Med Chem. 2005. PMID: 15755637

2

6-[2-(Phosphonomethoxy)alkoxy]pyrimidines with antiviral activity.

Holý A, Votruba I, Masojídková M, Andrei G, Snoeck R, Naesens L, De Clercq E, Balzarini J. Holý A, et al. J Med Chem. 2002 Apr 25;45(9):1918-29. doi: 10.1021/jm011095y. J Med Chem. 2002. PMID: 11960502

3

5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]pyrimidines-acyclic nucleoside phosphonate analogues with antiviral activity.

Hocková D, Holý A, Masojídková M, Andrei G, Snoeck R, De Clercq E, Balzarini J. Hocková D, et al. Among authors: holy a. J Med Chem. 2003 Nov 6;46(23):5064-73. doi: 10.1021/jm030932o. J Med Chem. 2003. PMID: 14584956

4

Synthesis of base substituted 2-hydroxy-3-(purin-9-yl)-propanoic acids and 4-(purin-9-yl)-3-butenoic acids.

Doláková P, Masojídková M, Holý A. Doláková P, et al. Among authors: holy a. Nucleosides Nucleotides Nucleic Acids. 2003 Dec;22(12):2145-60. doi: 10.1081/ncn-120026636. Nucleosides Nucleotides Nucleic Acids. 2003. PMID: 14714763

5

Synthesis and antiproliferative activity of 2,6-diamino-9-benzyl-9-deazapurine and related compounds.

Otmar M, Masojídková M, Votruba I, Holý A. Otmar M, et al. Among authors: holy a. Bioorg Med Chem. 2004 Jun 15;12(12):3187-95. doi: 10.1016/j.bmc.2004.04.003. Bioorg Med Chem. 2004. PMID: 15158786

6

Synthesis and antiviral activity of 2,4-diamino-5-cyano-6-[2-(phosphonomethoxy)ethoxy]pyrimidine and related compounds.

Hocková D, Holý A, Masojídková M, Andrei G, Snoeck R, De Clercq E, Balzarini J. Hocková D, et al. Among authors: holy a. Bioorg Med Chem. 2004 Jun 15;12(12):3197-202. doi: 10.1016/j.bmc.2004.04.002. Bioorg Med Chem. 2004. PMID: 15158787

7

Synthesis of 9-alkyl and 9-heteroalkyl substituted 2-amino-6-guanidinopurines and their influence on the NO-production in macrophages.

Cesnek M, Holý A, Masojídková M, Zídek Z. Cesnek M, et al. Among authors: holy a. Bioorg Med Chem. 2005 Apr 15;13(8):2917-26. doi: 10.1016/j.bmc.2005.02.008. Bioorg Med Chem. 2005. PMID: 15781401

8

Design and synthesis of novel 5,6-disubstituted uracil derivatives as potent inhibitors of thymidine phosphorylase.

Nencka R, Votruba I, Hrebabecký H, Tloust'ová E, Horská K, Masojídková M, Holý A. Nencka R, et al. Among authors: holy a. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1335-7. doi: 10.1016/j.bmcl.2005.11.050. Epub 2005 Dec 5. Bioorg Med Chem Lett. 2006. PMID: 16337119

9

Purine P1 receptor-dependent immunostimulatory effects of antiviral acyclic analogues of adenine and 2,6-diaminopurine.

Kmonícková E, Potmesil P, Holý A, Zídek Z. Kmonícková E, et al. Among authors: holy a. Eur J Pharmacol. 2006 Jan 13;530(1-2):179-87. doi: 10.1016/j.ejphar.2005.11.037. Epub 2005 Dec 20. Eur J Pharmacol. 2006. PMID: 16371225

10

Nucleotide analogues with immunobiological properties: 9-[2-Hydroxy-3-(phosphonomethoxy)propyl]-adenine (HPMPA), -2,6-diaminopurine (HPMPDAP), and their N6-substituted derivatives.

Potmesil P, Krecmerová M, Kmonícková E, Holý A, Zídek Z. Potmesil P, et al. Among authors: holy a. Eur J Pharmacol. 2006 Jul 1;540(1-3):191-9. doi: 10.1016/j.ejphar.2006.04.018. Epub 2006 Apr 27. Eur J Pharmacol. 2006. PMID: 16733050

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