Martínek V - Search Results

1

Expression of cytochrome P450 1A1 and its contribution to oxidation of a potential human carcinogen 1-phenylazo-2-naphthol (Sudan I) in human livers.

Stiborová M, Martínek V, Rýdlová H, Koblas T, Hodek P. Stiborová M, et al. Among authors: martinek v. Cancer Lett. 2005 Apr 8;220(2):145-54. doi: 10.1016/j.canlet.2004.07.036. Cancer Lett. 2005. PMID: 15766589

2

Sudan I is a potential carcinogen for humans: evidence for its metabolic activation and detoxication by human recombinant cytochrome P450 1A1 and liver microsomes.

Stiborová M, Martínek V, Rýdlová H, Hodek P, Frei E. Stiborová M, et al. Among authors: martinek v. Cancer Res. 2002 Oct 15;62(20):5678-84. Cancer Res. 2002. PMID: 12384524

3

Modulation of CYP1A1-mediated oxidation of carcinogenic azo dye Sudan I and its binding to DNA by cytochrome b5.

Stiborová M, Martínek V, Schmeiser HH, Frei E. Stiborová M, et al. Among authors: martinek v. Neuro Endocrinol Lett. 2006 Dec;27 Suppl 2:35-9. Neuro Endocrinol Lett. 2006. PMID: 17159775

4

A one-electron oxidation of carcinogenic nonaminoazo dye Sudan I by horseradish peroxidase.

Semanska M, Dracinsky M, Martinek V, Hudecek J, Hodek P, Frei E, Stiborova M. Semanska M, et al. Among authors: martinek v. Neuro Endocrinol Lett. 2008 Oct;29(5):712-6. Neuro Endocrinol Lett. 2008. PMID: 18987613

5

Cytochrome b(5) shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy.

Kotrbová V, Mrázová B, Moserová M, Martínek V, Hodek P, Hudeček J, Frei E, Stiborová M. Kotrbová V, et al. Among authors: martinek v. Biochem Pharmacol. 2011 Sep 15;82(6):669-80. doi: 10.1016/j.bcp.2011.06.003. Epub 2011 Jun 13. Biochem Pharmacol. 2011. PMID: 21683692

6

Induced expression of cytochrome P450 1A and NAD(P)H:quinone oxidoreductase determined at mRNA, protein, and enzyme activity levels in rats exposed to the carcinogenic azo dye 1-phenylazo-2-naphthol (Sudan I).

Stiborová M, Dračínská H, Martínek V, Svášková D, Hodek P, Milichovský J, Hejduková Ž, Brotánek J, Schmeiser HH, Frei E. Stiborová M, et al. Among authors: martinek v. Chem Res Toxicol. 2013 Feb 18;26(2):290-9. doi: 10.1021/tx3004533. Epub 2013 Jan 15. Chem Res Toxicol. 2013. PMID: 23289503

7

Theoretical investigation of differences in nitroreduction of aristolochic acid I by cytochromes P450 1A1, 1A2 and 1B1.

Jerabek P, Martinek V, Stiborova M. Jerabek P, et al. Among authors: martinek v. Neuro Endocrinol Lett. 2012;33 Suppl 3:25-32. Neuro Endocrinol Lett. 2012. PMID: 23353840

8

Enzymes oxidizing the azo dye 1-phenylazo-2-naphthol (Sudan I) and their contribution to its genotoxicity and carcinogenicity.

Stiborova M, Schmeiser HH, Frei E, Hodek P, Martinek V. Stiborova M, et al. Among authors: martinek v. Curr Drug Metab. 2014;15(8):829-40. doi: 10.2174/1389200216666150206125442. Curr Drug Metab. 2014. PMID: 25658126 Review.

9

A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches.

Stiborová M, Bárta F, Levová K, Hodek P, Schmeiser HH, Arlt VM, Martínek V. Stiborová M, et al. Among authors: martinek v. Int J Mol Sci. 2015 Nov 18;16(11):27561-75. doi: 10.3390/ijms161126047. Int J Mol Sci. 2015. PMID: 26593908 Free PMC article.

10

Preparation of a biologically active apo-cytochrome b5 via heterologous expression in Escherichia coli.

Kotrbová V, Aimová D, Ingr M, Borek-Dohalská L, Martínek V, Stiborová M. Kotrbová V, et al. Among authors: martinek v. Protein Expr Purif. 2009 Aug;66(2):203-9. doi: 10.1016/j.pep.2009.03.011. Epub 2009 Apr 7. Protein Expr Purif. 2009. PMID: 19358889

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