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Novel indolylindazolylmaleimides as inhibitors of protein kinase C-beta: synthesis, biological activity, and cardiovascular safety.
Zhang HC, Derian CK, McComsey DF, White KB, Ye H, Hecker LR, Li J, Addo MF, Croll D, Eckardt AJ, Smith CE, Li Q, Cheung WM, Conway BR, Emanuel S, Demarest KT, Andrade-Gordon P, Damiano BP, Maryanoff BE. Zhang HC, et al. Among authors: eckardt aj. J Med Chem. 2005 Mar 24;48(6):1725-8. doi: 10.1021/jm049478u. J Med Chem. 2005. PMID: 15771419
A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo.
de Garavilla L, Greco MN, Sukumar N, Chen ZW, Pineda AO, Mathews FS, Di Cera E, Giardino EC, Wells GI, Haertlein BJ, Kauffman JA, Corcoran TW, Derian CK, Eckardt AJ, Damiano BP, Andrade-Gordon P, Maryanoff BE. de Garavilla L, et al. Among authors: eckardt aj. J Biol Chem. 2005 May 6;280(18):18001-7. doi: 10.1074/jbc.M501302200. Epub 2005 Feb 28. J Biol Chem. 2005. PMID: 15741158 Free article.
Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor.
Andrade-Gordon P, Maryanoff BE, Derian CK, Zhang HC, Addo MF, Darrow AL, Eckardt AJ, Hoekstra WJ, McComsey DF, Oksenberg D, Reynolds EE, Santulli RJ, Scarborough RM, Smith CE, White KB. Andrade-Gordon P, et al. Among authors: eckardt aj. Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12257-62. doi: 10.1073/pnas.96.22.12257. Proc Natl Acad Sci U S A. 1999. PMID: 10535908 Free PMC article.
Administration of a potent antagonist of protease-activated receptor-1 (PAR-1) attenuates vascular restenosis following balloon angioplasty in rats.
Andrade-Gordon P, Derian CK, Maryanoff BE, Zhang HC, Addo MF, Cheung Wm, Damiano BP, D'Andrea MR, Darrow AL, de Garavilla L, Eckardt AJ, Giardino EC, Haertlein BJ, McComsey DF. Andrade-Gordon P, et al. Among authors: eckardt aj. J Pharmacol Exp Ther. 2001 Jul;298(1):34-42. J Pharmacol Exp Ther. 2001. PMID: 11408522
69 results