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Homozygosity for the CARD15 frameshift mutation 1007fs is predictive of early onset of Crohn's disease with ileal stenosis, entero-enteral fistulas, and frequent need for surgical intervention with high risk of re-stenosis.
Seiderer J, Schnitzler F, Brand S, Staudinger T, Pfennig S, Herrmann K, Hofbauer K, Dambacher J, Tillack C, Sackmann M, Göke B, Lohse P, Ochsenkühn T. Seiderer J, et al. Among authors: herrmann k. Scand J Gastroenterol. 2006 Dec;41(12):1421-32. doi: 10.1080/00365520600703900. Scand J Gastroenterol. 2006. PMID: 17101573
Benefits and challenges in bowel MR imaging at 3.0 T.
Herrmann KA, Paspulati RM, Lauenstein T, Reiser MF. Herrmann KA, et al. Top Magn Reson Imaging. 2010 Jun;21(3):165-75. doi: 10.1097/RMR.0b013e31822a3294. Top Magn Reson Imaging. 2010. PMID: 21847036 Review.
The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn's disease independent of the IL23R genotype.
Jürgens M, Brand S, Laubender RP, Seiderer J, Glas J, Wetzke M, Wagner J, Pfennig S, Tillack C, Beigel F, Weidinger M, Schnitzler F, Kreis ME, Göke B, Lohse P, Herrmann K, Ochsenkühn T. Jürgens M, et al. Among authors: herrmann k. J Gastroenterol. 2010 Jul;45(7):721-31. doi: 10.1007/s00535-010-0231-7. Epub 2010 Apr 29. J Gastroenterol. 2010. PMID: 20428899
1,410 results