Huang R - Search Results

1

Linking tumor cell cytotoxicity to mechanism of drug action: an integrated analysis of gene expression, small-molecule screening and structural databases.

Covell DG, Wallqvist A, Huang R, Thanki N, Rabow AA, Lu XJ. Covell DG, et al. Among authors: huang r. Proteins. 2005 May 15;59(3):403-33. doi: 10.1002/prot.20392. Proteins. 2005. PMID: 15778971 Review.

2

Anticancer metal compounds in NCI's tumor-screening database: putative mode of action.

Huang R, Wallqvist A, Covell DG. Huang R, et al. Biochem Pharmacol. 2005 Apr 1;69(7):1009-39. doi: 10.1016/j.bcp.2005.01.001. Biochem Pharmacol. 2005. PMID: 15763539 Review.

3

Comprehensive analysis of pathway or functionally related gene expression in the National Cancer Institute's anticancer screen.

Huang R, Wallqvist A, Covell DG. Huang R, et al. Genomics. 2006 Mar;87(3):315-28. doi: 10.1016/j.ygeno.2005.11.011. Epub 2006 Jan 4. Genomics. 2006. PMID: 16386875 Free article.

4

Evaluating chemical structure similarity as an indicator of cellular growth inhibition.

Wallqvist A, Huang R, Thanki N, Covell DG. Wallqvist A, et al. Among authors: huang r. J Chem Inf Model. 2006 Jan-Feb;46(1):430-7. doi: 10.1021/ci0501544. J Chem Inf Model. 2006. PMID: 16426077

5

Assessment of in vitro and in vivo activities in the National Cancer Institute's anticancer screen with respect to chemical structure, target specificity, and mechanism of action.

Huang R, Wallqvist A, Covell DG. Huang R, et al. J Med Chem. 2006 Mar 23;49(6):1964-79. doi: 10.1021/jm051029m. J Med Chem. 2006. PMID: 16539384

6

Targeting changes in cancer: assessing pathway stability by comparing pathway gene expression coherence levels in tumor and normal tissues.

Huang R, Wallqvist A, Covell DG. Huang R, et al. Mol Cancer Ther. 2006 Sep;5(9):2417-27. doi: 10.1158/1535-7163.MCT-06-0239. Mol Cancer Ther. 2006. PMID: 16985076

7

Chemoinformatic analysis of NCI preclinical tumor data: evaluating compound efficacy from mouse xenograft data, NCI-60 screening data, and compound descriptors.

Wallqvist A, Huang R, Covell DG. Wallqvist A, et al. Among authors: huang r. J Chem Inf Model. 2007 Jul-Aug;47(4):1414-27. doi: 10.1021/ci700132u. Epub 2007 Jun 8. J Chem Inf Model. 2007. PMID: 17555311

8

Anticancer medicines in development: assessment of bioactivity profiles within the National Cancer Institute anticancer screening data.

Covell DG, Huang R, Wallqvist A. Covell DG, et al. Among authors: huang r. Mol Cancer Ther. 2007 Aug;6(8):2261-70. doi: 10.1158/1535-7163.MCT-06-0787. Mol Cancer Ther. 2007. PMID: 17699723

9

Drugs aimed at targeting characteristic karyotypic phenotypes of cancer cells.

Wallqvist A, Huang R, Covell DG, Roschke AV, Gelhaus KS, Kirsch IR. Wallqvist A, et al. Among authors: huang r. Mol Cancer Ther. 2005 Oct;4(10):1559-68. doi: 10.1158/1535-7163.MCT-05-0224. Mol Cancer Ther. 2005. PMID: 16227406

10

Cytotoxicity of RH1: NAD(P)H:quinone acceptor oxidoreductase (NQO1)-independent oxidative stress and apoptosis induction.

Tudor G, Alley M, Nelson CM, Huang R, Covell DG, Gutierrez P, Sausville EA. Tudor G, et al. Among authors: huang r. Anticancer Drugs. 2005 Apr;16(4):381-91. doi: 10.1097/00001813-200504000-00004. Anticancer Drugs. 2005. PMID: 15746574

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