Winstanley P - Search Results

1

Why has the dihydrofolate reductase 164 mutation not consistently been found in Africa yet?

Nzila A, Ochong E, Nduati E, Gilbert K, Winstanley P, Ward S, Marsh K. Nzila A, et al. Among authors: winstanley p. Trans R Soc Trop Med Hyg. 2005 May;99(5):341-6. doi: 10.1016/j.trstmh.2004.07.002. Trans R Soc Trop Med Hyg. 2005. PMID: 15780340 Review.

2

Chemosensitization of Plasmodium falciparum by probenecid in vitro.

Nzila A, Mberu E, Bray P, Kokwaro G, Winstanley P, Marsh K, Ward S. Nzila A, et al. Among authors: winstanley p. Antimicrob Agents Chemother. 2003 Jul;47(7):2108-12. doi: 10.1128/AAC.47.7.2108-2112.2003. Antimicrob Agents Chemother. 2003. PMID: 12821454 Free PMC article.

3

Therapeutic potential of folate uptake inhibition in Plasmodium falciparum.

Nzila AM, Kokwaro G, Winstanley PA, Marsh K, Ward SA. Nzila AM, et al. Trends Parasitol. 2004 Mar;20(3):109-12. doi: 10.1016/j.pt.2003.12.005. Trends Parasitol. 2004. PMID: 16676416 Review.

4

Chlorproguanil/dapsone for uncomplicated Plasmodium falciparum malaria in young children: pharmacokinetics and therapeutic range.

Winstanley P, Watkins W, Muhia D, Szwandt S, Amukoye E, Marsh K. Winstanley P, et al. Trans R Soc Trop Med Hyg. 1997 May-Jun;91(3):322-7. doi: 10.1016/s0035-9203(97)90093-6. Trans R Soc Trop Med Hyg. 1997. PMID: 9231209

5

A single dose of intramuscular sulfadoxine-pyrimethamine as an adjunct to quinine in the treatment of severe malaria: pharmacokinetics and efficacy.

Newton CR, Winstanley PA, Watkins WM, Mwangi IN, Waruiru CM, Mberu EK, Warn PA, Nevill CG, Marsh K. Newton CR, et al. Among authors: winstanley pa. Trans R Soc Trop Med Hyg. 1993 Mar-Apr;87(2):207-10. doi: 10.1016/0035-9203(93)90495-c. Trans R Soc Trop Med Hyg. 1993. PMID: 8337731 Clinical Trial.

6

Quinine sensitivity of isolates of Plasmodium falciparum from the coast of Kenya.

Haruki K, Winstanley PA, Watkins WM, Marsh K. Haruki K, et al. Among authors: winstanley pa. Trans R Soc Trop Med Hyg. 1998 Mar-Apr;92(2):195-6. doi: 10.1016/s0035-9203(98)90746-5. Trans R Soc Trop Med Hyg. 1998. PMID: 9764332 No abstract available.

7

Towards an understanding of the mechanism of pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: genotyping of dihydrofolate reductase and dihydropteroate synthase of Kenyan parasites.

Nzila AM, Mberu EK, Sulo J, Dayo H, Winstanley PA, Sibley CH, Watkins WM. Nzila AM, et al. Among authors: winstanley pa. Antimicrob Agents Chemother. 2000 Apr;44(4):991-6. doi: 10.1128/AAC.44.4.991-996.2000. Antimicrob Agents Chemother. 2000. PMID: 10722502 Free PMC article.

8

Molecular evidence of greater selective pressure for drug resistance exerted by the long-acting antifolate Pyrimethamine/Sulfadoxine compared with the shorter-acting chlorproguanil/dapsone on Kenyan Plasmodium falciparum.

Nzila AM, Nduati E, Mberu EK, Hopkins Sibley C, Monks SA, Winstanley PA, Watkins WM. Nzila AM, et al. Among authors: winstanley pa. J Infect Dis. 2000 Jun;181(6):2023-8. doi: 10.1086/315520. Epub 2000 Jun 5. J Infect Dis. 2000. PMID: 10837185

9

Plasmodium falciparum strains harboring dihydrofolate reductase with the I164L mutation are absent in Malawi and Zambia even under antifolate drug pressure.

Ochong E, Bell DJ, Johnson DJ, D'Alessandro U, Mulenga M, Muangnoicharoen S, Van Geertruyden JP, Winstanley PA, Bray PG, Ward SA, Owen A. Ochong E, et al. Antimicrob Agents Chemother. 2008 Nov;52(11):3883-8. doi: 10.1128/AAC.00431-08. Epub 2008 Aug 25. Antimicrob Agents Chemother. 2008. PMID: 18725445 Free PMC article.

10

Chlorproguanil-dapsone for treatment of drug-resistant falciparum malaria in Tanzania.

Mutabingwa T, Nzila A, Mberu E, Nduati E, Winstanley P, Hills E, Watkins W. Mutabingwa T, et al. Among authors: winstanley p. Lancet. 2001 Oct 13;358(9289):1218-23. doi: 10.1016/S0140-6736(01)06344-9. Lancet. 2001. PMID: 11675058

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