Mehta AB - Search Results

1

Selective apoptotic killing of malignant hemopoietic cells by antibody-targeted delivery of an amphipathic peptide.

Marks AJ, Cooper MS, Anderson RJ, Orchard KH, Hale G, North JM, Ganeshaguru K, Steele AJ, Mehta AB, Lowdell MW, Wickremasinghe RG. Marks AJ, et al. Among authors: mehta ab. Cancer Res. 2005 Mar 15;65(6):2373-7. doi: 10.1158/0008-5472.CAN-04-2594. Cancer Res. 2005. PMID: 15781652 Free article.

2

Geldanamycin and herbimycin A induce apoptotic killing of B chronic lymphocytic leukemia cells and augment the cells' sensitivity to cytotoxic drugs.

Jones DT, Addison E, North JM, Lowdell MW, Hoffbrand AV, Mehta AB, Ganeshaguru K, Folarin NI, Wickremasinghe RG. Jones DT, et al. Among authors: mehta ab. Blood. 2004 Mar 1;103(5):1855-61. doi: 10.1182/blood-2003-05-1603. Epub 2003 Oct 23. Blood. 2004. PMID: 14576064 Free article.

3

Actions of the selective protein kinase C inhibitor PKC412 on B-chronic lymphocytic leukemia cells in vitro.

Ganeshaguru K, Wickremasinghe RG, Jones DT, Gordon M, Hart SM, Virchis AE, Prentice HG, Hoffbrand AV, Man A, Champain K, Csermak K, Mehta AB. Ganeshaguru K, et al. Among authors: mehta ab. Haematologica. 2002 Feb;87(2):167-76. Haematologica. 2002. PMID: 11836167

4

Albumin activates the AKT signaling pathway and protects B-chronic lymphocytic leukemia cells from chlorambucil- and radiation-induced apoptosis.

Jones DT, Ganeshaguru K, Anderson RJ, Jackson TR, Bruckdorfer KR, Low SY, Palmqvist L, Prentice HG, Hoffbrand AV, Mehta AB, Wickremasinghe RG. Jones DT, et al. Among authors: mehta ab. Blood. 2003 Apr 15;101(8):3174-80. doi: 10.1182/blood-2002-07-2143. Epub 2002 Dec 12. Blood. 2003. PMID: 12480711 Free article.

5

Cytotoxic drugs enhance the ex vivo sensitivity of malignant cells from a subset of acute myeloid leukaemia patients to apoptosis induction by tumour necrosis factor receptor-related apoptosis-inducing ligand.

Jones DT, Ganeshaguru K, Mitchell WA, Foroni L, Baker RJ, Prentice HG, Mehta AB, Wickremasinghe RG. Jones DT, et al. Among authors: mehta ab. Br J Haematol. 2003 Jun;121(5):713-20. doi: 10.1046/j.1365-2141.2003.04340.x. Br J Haematol. 2003. PMID: 12780785 Free article.

6

Glucosylceramide synthase inhibitors sensitise CLL cells to cytotoxic agents without reversing P-gp functional activity.

Gerrard G, Butters TD, Ganeshaguru K, Mehta AB. Gerrard G, et al. Among authors: mehta ab. Eur J Pharmacol. 2009 May 1;609(1-3):34-9. doi: 10.1016/j.ejphar.2009.03.018. Epub 2009 Mar 12. Eur J Pharmacol. 2009. PMID: 19285492

7

MK 886, an antagonist of leukotriene generation, inhibits DNA synthesis in a subset of acute myeloid leukaemia cells.

Khan MA, Hoffbrand AV, Mehta A, Wright F, Tahami F, Wickremasinghe RG. Khan MA, et al. Leuk Res. 1993 Sep;17(9):759-62. doi: 10.1016/0145-2126(93)90109-x. Leuk Res. 1993. PMID: 8371575

8

Clinical effects and P-glycoprotein inhibition in patients with acute myeloid leukemia treated with zosuquidar trihydrochloride, daunorubicin and cytarabine.

Gerrard G, Payne E, Baker RJ, Jones DT, Potter M, Prentice HG, Ethell M, McCullough H, Burgess M, Mehta AB, Ganeshaguru K. Gerrard G, et al. Among authors: mehta ab. Haematologica. 2004 Jul;89(7):782-90. Haematologica. 2004. PMID: 15257929 Clinical Trial.

9

A novel treatment approach for low grade lymphoproliferative disorders using PKC412 (CGP41251), an inhibitor of protein kinase C.

Virchis A, Ganeshaguru K, Hart S, Jones D, Fletcher L, Wright F, Wickremasinghe R, Man A, Csermak K, Meyer T, Fabbro D, Champain K, Yap A, Prentice HG, Mehta A. Virchis A, et al. Hematol J. 2002;3(3):131-6. doi: 10.1038/sj.thj.6200165. Hematol J. 2002. PMID: 12111648 Clinical Trial.

10

Cytogenetics of multiple myeloma: interpretation of fluorescence in situ hybridization results.

Harrison CJ, Mazzullo H, Cheung KL, Gerrard G, Jalali GR, Mehta A, Osier DG, Orchard KH. Harrison CJ, et al. Br J Haematol. 2003 Mar;120(6):944-52. doi: 10.1046/j.1365-2141.2003.04172.x. Br J Haematol. 2003. PMID: 12648063 Free article.

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