Aubin Y - Search Results

1

Discovery, biosynthesis, and structure elucidation of new metabolites of norandrostenedione using in vitro systems.

Lévesque JF, Gaudreault M, Aubin Y, Chauret N. Lévesque JF, et al. Among authors: aubin y. Steroids. 2005 Apr;70(4):305-17. doi: 10.1016/j.steroids.2004.12.005. Steroids. 2005. PMID: 15784285

2

In vitro biotransformations of the prostaglandin D2 (DP) antagonist MK-0524 and synthesis of metabolites.

Nicoll-Griffith DA, Seto C, Aubin Y, Lévesque JF, Chauret N, Day S, Silva JM, Trimble LA, Truchon JF, Berthelette C, Lachance N, Wang Z, Sturino C, Braun M, Zamboni R, Young RN. Nicoll-Griffith DA, et al. Among authors: aubin y. Bioorg Med Chem Lett. 2007 Jan 15;17(2):301-4. doi: 10.1016/j.bmcl.2006.10.055. Epub 2006 Oct 25. Bioorg Med Chem Lett. 2007. PMID: 17095220

3

Discovery of a potent and selective COX-2 inhibitor in the alkoxy lactone series with optimized metabolic profile.

Leblanc Y, Roy P, Wang Z, Li CS, Chauret N, Nicoll-Griffith DA, Silva JM, Aubin Y, Yergey JA, Chan CC, Riendeau D, Brideau C, Gordon R, Xu L, Webb J, Visco DM, Prasit P. Leblanc Y, et al. Among authors: aubin y. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3317-20. doi: 10.1016/s0960-894x(02)00739-4. Bioorg Med Chem Lett. 2002. PMID: 12392741

4

Discovery of a potent and selective prostaglandin D2 receptor antagonist, [(3R)-4-(4-chloro-benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid (MK-0524).

Sturino CF, O'Neill G, Lachance N, Boyd M, Berthelette C, Labelle M, Li L, Roy B, Scheigetz J, Tsou N, Aubin Y, Bateman KP, Chauret N, Day SH, Lévesque JF, Seto C, Silva JH, Trimble LA, Carriere MC, Denis D, Greig G, Kargman S, Lamontagne S, Mathieu MC, Sawyer N, Slipetz D, Abraham WM, Jones T, McAuliffe M, Piechuta H, Nicoll-Griffith DA, Wang Z, Zamboni R, Young RN, Metters KM. Sturino CF, et al. Among authors: aubin y. J Med Chem. 2007 Feb 22;50(4):794-806. doi: 10.1021/jm0603668. J Med Chem. 2007. PMID: 17300164

5

Novel, nonpeptidic cyanamides as potent and reversible inhibitors of human cathepsins K and L.

Falgueyret JP, Oballa RM, Okamoto O, Wesolowski G, Aubin Y, Rydzewski RM, Prasit P, Riendeau D, Rodan SB, Percival MD. Falgueyret JP, et al. Among authors: aubin y. J Med Chem. 2001 Jan 4;44(1):94-104. doi: 10.1021/jm0003440. J Med Chem. 2001. PMID: 11141092

6

Hsp60 accelerates the maturation of pro-caspase-3 by upstream activator proteases during apoptosis.

Xanthoudakis S, Roy S, Rasper D, Hennessey T, Aubin Y, Cassady R, Tawa P, Ruel R, Rosen A, Nicholson DW. Xanthoudakis S, et al. Among authors: aubin y. EMBO J. 1999 Apr 15;18(8):2049-56. doi: 10.1093/emboj/18.8.2049. EMBO J. 1999. PMID: 10205159 Free PMC article.

7

Interactions between the conserved hydrophobic region of the prion protein and dodecylphosphocholine micelles.

Sauvé S, Buijs D, Gingras G, Aubin Y. Sauvé S, et al. Among authors: aubin y. J Biol Chem. 2012 Jan 13;287(3):1915-22. doi: 10.1074/jbc.M111.279364. Epub 2011 Nov 29. J Biol Chem. 2012. PMID: 22128151 Free PMC article.

8

A single N-acetylgalactosamine residue at threonine 106 modifies the dynamics and structure of interferon α2a around the glycosylation site.

Ghasriani H, Belcourt PJ, Sauvé S, Hodgson DJ, Brochu D, Gilbert M, Aubin Y. Ghasriani H, et al. Among authors: aubin y. J Biol Chem. 2013 Jan 4;288(1):247-54. doi: 10.1074/jbc.M112.413252. Epub 2012 Nov 26. J Biol Chem. 2013. PMID: 23184955 Free PMC article.

9

Dodecylphosphocholine Micelles Induce Amyloid Formation of the PrP(110-136) Peptide via an α-Helical Metastable Conformation.

Sauvé S, Aubin Y. Sauvé S, et al. Among authors: aubin y. PLoS One. 2016 Dec 8;11(12):e0168021. doi: 10.1371/journal.pone.0168021. eCollection 2016. PLoS One. 2016. PMID: 27930722 Free PMC article.

10

NMR assignment of human granulocyte-macrophage colony-stimulating factor.

Sauvé S, Gingras G, Aubin Y. Sauvé S, et al. Among authors: aubin y. Biomol NMR Assign. 2008 Jun;2(1):5-7. doi: 10.1007/s12104-007-9070-8. Epub 2007 Dec 8. Biomol NMR Assign. 2008. PMID: 19636911

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