Speck NA - Search Results

1

Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype.

Growney JD, Shigematsu H, Li Z, Lee BH, Adelsperger J, Rowan R, Curley DP, Kutok JL, Akashi K, Williams IR, Speck NA, Gilliland DG. Growney JD, et al. Among authors: speck na. Blood. 2005 Jul 15;106(2):494-504. doi: 10.1182/blood-2004-08-3280. Epub 2005 Mar 22. Blood. 2005. PMID: 15784726 Free PMC article.

2

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia.

Song WJ, Sullivan MG, Legare RD, Hutchings S, Tan X, Kufrin D, Ratajczak J, Resende IC, Haworth C, Hock R, Loh M, Felix C, Roy DC, Busque L, Kurnit D, Willman C, Gewirtz AM, Speck NA, Bushweller JH, Li FP, Gardiner K, Poncz M, Maris JM, Gilliland DG. Song WJ, et al. Among authors: speck na. Nat Genet. 1999 Oct;23(2):166-75. doi: 10.1038/13793. Nat Genet. 1999. PMID: 10508512

3

The leukemia-associated AML1 (Runx1)--CBF beta complex functions as a DNA-induced molecular clamp.

Bravo J, Li Z, Speck NA, Warren AJ. Bravo J, et al. Among authors: speck na. Nat Struct Biol. 2001 Apr;8(4):371-8. doi: 10.1038/86264. Nat Struct Biol. 2001. PMID: 11276260

4

Core-binding factor beta (CBFbeta), but not CBFbeta-smooth muscle myosin heavy chain, rescues definitive hematopoiesis in CBFbeta-deficient embryonic stem cells.

Miller JD, Stacy T, Liu PP, Speck NA. Miller JD, et al. Among authors: speck na. Blood. 2001 Apr 15;97(8):2248-56. doi: 10.1182/blood.v97.8.2248. Blood. 2001. PMID: 11290585 Free article.

5

Runx1 is essential for hematopoietic commitment at the hemangioblast stage of development in vitro.

Lacaud G, Gore L, Kennedy M, Kouskoff V, Kingsley P, Hogan C, Carlsson L, Speck N, Palis J, Keller G. Lacaud G, et al. Blood. 2002 Jul 15;100(2):458-66. doi: 10.1182/blood-2001-12-0321. Blood. 2002. PMID: 12091336 Free article.

6

Core-binding factors in haematopoiesis and leukaemia.

Speck NA, Gilliland DG. Speck NA, et al. Nat Rev Cancer. 2002 Jul;2(7):502-13. doi: 10.1038/nrc840. Nat Rev Cancer. 2002. PMID: 12094236 Review. No abstract available.

7

Energetic contribution of residues in the Runx1 Runt domain to DNA binding.

Li Z, Yan J, Matheny CJ, Corpora T, Bravo J, Warren AJ, Bushweller JH, Speck NA. Li Z, et al. Among authors: speck na. J Biol Chem. 2003 Aug 29;278(35):33088-96. doi: 10.1074/jbc.M303973200. Epub 2003 Jun 13. J Biol Chem. 2003. PMID: 12807882 Free article.

8

Possible roles of Runx1 and Sox9 in incipient intramembranous ossification.

Yamashiro T, Wang XP, Li Z, Oya S, Aberg T, Fukunaga T, Kamioka H, Speck NA, Takano-Yamamoto T, Thesleff I. Yamashiro T, et al. Among authors: speck na. J Bone Miner Res. 2004 Oct;19(10):1671-7. doi: 10.1359/JBMR.040801. Epub 2004 Aug 3. J Bone Miner Res. 2004. PMID: 15355562 Free article.

9

Runx1 deficiency predisposes mice to T-lymphoblastic lymphoma.

Kundu M, Compton S, Garrett-Beal L, Stacy T, Starost MF, Eckhaus M, Speck NA, Liu PP. Kundu M, et al. Among authors: speck na. Blood. 2005 Nov 15;106(10):3621-4. doi: 10.1182/blood-2005-04-1447. Epub 2005 Jul 28. Blood. 2005. PMID: 16051740 Free PMC article.

10

Runx1 function in hematopoiesis is required in cells that express Tek.

Li Z, Chen MJ, Stacy T, Speck NA. Li Z, et al. Among authors: speck na. Blood. 2006 Jan 1;107(1):106-10. doi: 10.1182/blood-2005-05-1955. Epub 2005 Sep 20. Blood. 2006. PMID: 16174759 Free PMC article.

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