Alessi DR - Search Results

1

Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis.

McManus EJ, Sakamoto K, Armit LJ, Ronaldson L, Shpiro N, Marquez R, Alessi DR. McManus EJ, et al. Among authors: alessi dr. EMBO J. 2005 Apr 20;24(8):1571-83. doi: 10.1038/sj.emboj.7600633. Epub 2005 Mar 24. EMBO J. 2005. PMID: 15791206 Free PMC article.

2

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf.

Cross DA, Alessi DR, Vandenheede JR, McDowell HE, Hundal HS, Cohen P. Cross DA, et al. Among authors: alessi dr. Biochem J. 1994 Oct 1;303 ( Pt 1)(Pt 1):21-6. doi: 10.1042/bj3030021. Biochem J. 1994. PMID: 7945242 Free PMC article.

3

Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1.

Alessi DR, Saito Y, Campbell DG, Cohen P, Sithanandam G, Rapp U, Ashworth A, Marshall CJ, Cowley S. Alessi DR, et al. EMBO J. 1994 Apr 1;13(7):1610-9. doi: 10.1002/j.1460-2075.1994.tb06424.x. EMBO J. 1994. PMID: 8157000 Free PMC article.

4

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B.

Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA. Cross DA, et al. Among authors: alessi dr. Nature. 1995 Dec 21-28;378(6559):785-9. doi: 10.1038/378785a0. Nature. 1995. PMID: 8524413

5

Mechanism of activation of protein kinase B by insulin and IGF-1.

Alessi DR, Andjelkovic M, Caudwell B, Cron P, Morrice N, Cohen P, Hemmings BA. Alessi DR, et al. EMBO J. 1996 Dec 2;15(23):6541-51. EMBO J. 1996. PMID: 8978681 Free PMC article.

6

Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase.

Alessi DR, Caudwell FB, Andjelkovic M, Hemmings BA, Cohen P. Alessi DR, et al. FEBS Lett. 1996 Dec 16;399(3):333-8. doi: 10.1016/s0014-5793(96)01370-1. FEBS Lett. 1996. PMID: 8985174 Free article.

7

PDK1, one of the missing links in insulin signal transduction?

Cohen P, Alessi DR, Cross DA. Cohen P, et al. Among authors: alessi dr. FEBS Lett. 1997 Jun 23;410(1):3-10. doi: 10.1016/s0014-5793(97)00490-0. FEBS Lett. 1997. PMID: 9247112 Free article. Review.

8

Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha.

Walker KS, Deak M, Paterson A, Hudson K, Cohen P, Alessi DR. Walker KS, et al. Among authors: alessi dr. Biochem J. 1998 Apr 1;331 ( Pt 1)(Pt 1):299-308. doi: 10.1042/bj3310299. Biochem J. 1998. PMID: 9512493 Free PMC article.

9

Mechanism of activation and function of protein kinase B.

Alessi DR, Cohen P. Alessi DR, et al. Curr Opin Genet Dev. 1998 Feb;8(1):55-62. doi: 10.1016/s0959-437x(98)80062-2. Curr Opin Genet Dev. 1998. PMID: 9529606 Review.

10

Constitutive activation of protein kinase B alpha by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen synthase kinase 3 in L6 muscle cells.

Hajduch E, Alessi DR, Hemmings BA, Hundal HS. Hajduch E, et al. Among authors: alessi dr. Diabetes. 1998 Jul;47(7):1006-13. doi: 10.2337/diabetes.47.7.1006. Diabetes. 1998. PMID: 9648821

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