Li L - Search Results

1

Internal tandem duplications of the FLT3 gene are present in leukemia stem cells.

Levis M, Murphy KM, Pham R, Kim KT, Stine A, Li L, McNiece I, Smith BD, Small D. Levis M, et al. Among authors: li l. Blood. 2005 Jul 15;106(2):673-80. doi: 10.1182/blood-2004-05-1902. Epub 2005 Mar 29. Blood. 2005. PMID: 15797998 Free PMC article.

2

Internal tandem duplication mutation of FLT3 blocks myeloid differentiation through suppression of C/EBPalpha expression.

Zheng R, Friedman AD, Levis M, Li L, Weir EG, Small D. Zheng R, et al. Among authors: li l. Blood. 2004 Mar 1;103(5):1883-90. doi: 10.1182/blood-2003-06-1978. Epub 2003 Oct 30. Blood. 2004. PMID: 14592841 Free article.

3

Transgenic mice expressing Tel-FLT3, a constitutively activated form of FLT3, develop myeloproliferative disease.

Baldwin BR, Li L, Tse KF, Small S, Collector M, Whartenby KA, Sharkis SJ, Racke F, Huso D, Small D. Baldwin BR, et al. Among authors: li l. Leukemia. 2007 Apr;21(4):764-71. doi: 10.1038/sj.leu.2404532. Epub 2007 Feb 1. Leukemia. 2007. PMID: 17268528

4

FLT3/ITD expression increases expansion, survival and entry into cell cycle of human haematopoietic stem/progenitor cells.

Li L, Piloto O, Kim KT, Ye Z, Nguyen HB, Yu X, Levis M, Cheng L, Small D. Li L, et al. Br J Haematol. 2007 Apr;137(1):64-75. doi: 10.1111/j.1365-2141.2007.06525.x. Br J Haematol. 2007. PMID: 17359372 Free article.

5

Constitutive Fms-like tyrosine kinase 3 activation results in specific changes in gene expression in myeloid leukaemic cells.

Kim KT, Baird K, Davis S, Piloto O, Levis M, Li L, Chen P, Meltzer P, Small D. Kim KT, et al. Among authors: li l. Br J Haematol. 2007 Sep;138(5):603-15. doi: 10.1111/j.1365-2141.2007.06696.x. Br J Haematol. 2007. PMID: 17686054 Free article.

6

Knock-in of an internal tandem duplication mutation into murine FLT3 confers myeloproliferative disease in a mouse model.

Li L, Piloto O, Nguyen HB, Greenberg K, Takamiya K, Racke F, Huso D, Small D. Li L, et al. Blood. 2008 Apr 1;111(7):3849-58. doi: 10.1182/blood-2007-08-109942. Epub 2008 Feb 1. Blood. 2008. PMID: 18245664 Free PMC article.

7

Cells expressing FLT3/ITD mutations exhibit elevated repair errors generated through alternative NHEJ pathways: implications for genomic instability and therapy.

Fan J, Li L, Small D, Rassool F. Fan J, et al. Among authors: li l. Blood. 2010 Dec 9;116(24):5298-305. doi: 10.1182/blood-2010-03-272591. Epub 2010 Aug 31. Blood. 2010. PMID: 20807885 Free PMC article.

8

Defective nonhomologous end joining blocks B-cell development in FLT3/ITD mice.

Li L, Zhang L, Fan J, Greenberg K, Desiderio S, Rassool FV, Small D. Li L, et al. Blood. 2011 Mar 17;117(11):3131-9. doi: 10.1182/blood-2010-05-286070. Epub 2011 Jan 12. Blood. 2011. PMID: 21228325 Free PMC article.

9

Loss of the wild-type allele contributes to myeloid expansion and disease aggressiveness in FLT3/ITD knockin mice.

Li L, Bailey E, Greenblatt S, Huso D, Small D. Li L, et al. Blood. 2011 Nov 3;118(18):4935-45. doi: 10.1182/blood-2011-01-328096. Epub 2011 Sep 8. Blood. 2011. PMID: 21908433 Free PMC article.

10

Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model.

Greenblatt S, Li L, Slape C, Nguyen B, Novak R, Duffield A, Huso D, Desiderio S, Borowitz MJ, Aplan P, Small D. Greenblatt S, et al. Among authors: li l. Blood. 2012 Mar 22;119(12):2883-94. doi: 10.1182/blood-2011-10-382283. Epub 2012 Feb 8. Blood. 2012. PMID: 22323452 Free PMC article.

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