Kosmehl H - Search Results

1

Engineered vascular-targeting antibody-interferon-gamma fusion protein for cancer therapy.

Ebbinghaus C, Ronca R, Kaspar M, Grabulovski D, Berndt A, Kosmehl H, Zardi L, Neri D. Ebbinghaus C, et al. Among authors: kosmehl h. Int J Cancer. 2005 Aug 20;116(2):304-13. doi: 10.1002/ijc.20952. Int J Cancer. 2005. PMID: 15800913

2

Synergistic therapeutic effects of a tumor targeting antibody fragment, fused to interleukin 12 and to tumor necrosis factor alpha.

Halin C, Gafner V, Villani ME, Borsi L, Berndt A, Kosmehl H, Zardi L, Neri D. Halin C, et al. Among authors: kosmehl h. Cancer Res. 2003 Jun 15;63(12):3202-10. Cancer Res. 2003. PMID: 12810649

3

Targeted delivery of tissue factor to the ED-B domain of fibronectin, a marker of angiogenesis, mediates the infarction of solid tumors in mice.

Nilsson F, Kosmehl H, Zardi L, Neri D. Nilsson F, et al. Among authors: kosmehl h. Cancer Res. 2001 Jan 15;61(2):711-6. Cancer Res. 2001. PMID: 11212273

4

Selective occlusion of tumor blood vessels by targeted delivery of an antibody-photosensitizer conjugate.

Fabbrini M, Trachsel E, Soldani P, Bindi S, Alessi P, Bracci L, Kosmehl H, Zardi L, Neri D, Neri P. Fabbrini M, et al. Among authors: kosmehl h. Int J Cancer. 2006 Apr 1;118(7):1805-13. doi: 10.1002/ijc.21412. Int J Cancer. 2006. PMID: 16217760

5

Antibody-mediated delivery of IL-10 inhibits the progression of established collagen-induced arthritis.

Trachsel E, Bootz F, Silacci M, Kaspar M, Kosmehl H, Neri D. Trachsel E, et al. Among authors: kosmehl h. Arthritis Res Ther. 2007;9(1):R9. doi: 10.1186/ar2115. Arthritis Res Ther. 2007. PMID: 17261171 Free PMC article.

6

Enhancement of the antitumor activity of interleukin-12 by targeted delivery to neovasculature.

Halin C, Rondini S, Nilsson F, Berndt A, Kosmehl H, Zardi L, Neri D. Halin C, et al. Among authors: kosmehl h. Nat Biotechnol. 2002 Mar;20(3):264-9. doi: 10.1038/nbt0302-264. Nat Biotechnol. 2002. PMID: 11875427

7

Selective targeted delivery of TNFalpha to tumor blood vessels.

Borsi L, Balza E, Carnemolla B, Sassi F, Castellani P, Berndt A, Kosmehl H, Biro A, Siri A, Orecchia P, Grassi J, Neri D, Zardi L. Borsi L, et al. Among authors: kosmehl h. Blood. 2003 Dec 15;102(13):4384-92. doi: 10.1182/blood-2003-04-1039. Epub 2003 Aug 21. Blood. 2003. PMID: 12933583 Free article.

8

Enhancement of the antitumor properties of interleukin-2 by its targeted delivery to the tumor blood vessel extracellular matrix.

Carnemolla B, Borsi L, Balza E, Castellani P, Meazza R, Berndt A, Ferrini S, Kosmehl H, Neri D, Zardi L. Carnemolla B, et al. Among authors: kosmehl h. Blood. 2002 Mar 1;99(5):1659-65. doi: 10.1182/blood.v99.5.1659. Blood. 2002. PMID: 11861281 Free article.

9

The tumour-targeting human L19-IL2 immunocytokine: preclinical safety studies, phase I clinical trial in patients with solid tumours and expansion into patients with advanced renal cell carcinoma.

Johannsen M, Spitaleri G, Curigliano G, Roigas J, Weikert S, Kempkensteffen C, Roemer A, Kloeters C, Rogalla P, Pecher G, Miller K, Berndt A, Kosmehl H, Trachsel E, Kaspar M, Lovato V, González-Iglesias R, Giovannoni L, Menssen HD, Neri D, de Braud F. Johannsen M, et al. Among authors: kosmehl h. Eur J Cancer. 2010 Nov;46(16):2926-35. doi: 10.1016/j.ejca.2010.07.033. Epub 2010 Aug 24. Eur J Cancer. 2010. PMID: 20797845 Clinical Trial.

10

Paclitaxel enhances therapeutic efficacy of the F8-IL2 immunocytokine to EDA-fibronectin-positive metastatic human melanoma xenografts.

Moschetta M, Pretto F, Berndt A, Galler K, Richter P, Bassi A, Oliva P, Micotti E, Valbusa G, Schwager K, Kaspar M, Trachsel E, Kosmehl H, Bani MR, Neri D, Giavazzi R. Moschetta M, et al. Among authors: kosmehl h. Cancer Res. 2012 Apr 1;72(7):1814-24. doi: 10.1158/0008-5472.CAN-11-1919. Epub 2012 Mar 5. Cancer Res. 2012. PMID: 22392081

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