Li S - Search Results

1

Discovery of bicycloalkyl urea melanin concentrating hormone receptor antagonists: orally efficacious antiobesity therapeutics.

McBriar MD, Guzik H, Xu R, Paruchova J, Li S, Palani A, Clader JW, Greenlee WJ, Hawes BE, Kowalski TJ, O'Neill K, Spar B, Weig B. McBriar MD, et al. Among authors: li s. J Med Chem. 2005 Apr 7;48(7):2274-7. doi: 10.1021/jm049035q. J Med Chem. 2005. PMID: 15801820

2

Muscarinic M2 antagonists: anthranilamide derivatives with exceptional selectivity and in vivo activity.

Clader JW, Billard W, Binch H 3rd, Chen LY, Crosby G Jr, Duffy RA, Ford J, Kozlowski JA, Lachowicz JE, Li S, Liu C, McCombie SW, Vice S, Zhou G, Greenlee WJ. Clader JW, et al. Among authors: li s. Bioorg Med Chem. 2004 Jan 15;12(2):319-26. doi: 10.1016/j.bmc.2003.11.005. Bioorg Med Chem. 2004. PMID: 14723952

3

Bicyclic[4.1.0]heptanes as phenyl replacements for melanin concentrating hormone receptor antagonists.

Xu R, Li S, Paruchova J, McBriar MD, Guzik H, Palani A, Clader JW, Cox K, Greenlee WJ, Hawes BE, Kowalski TJ, O'Neill K, Spar BD, Weig B, Weston DJ. Xu R, et al. Among authors: li s. Bioorg Med Chem. 2006 May 15;14(10):3285-99. doi: 10.1016/j.bmc.2005.12.046. Epub 2006 Jan 26. Bioorg Med Chem. 2006. PMID: 16442800

4

(Phenylpiperazinyl)cyclohexylureas: discovery of alpha1a/1d-selective adrenergic receptor antagonists for the treatment of benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS).

Chiu G, Li S, Connolly PJ, Pulito V, Liu J, Middleton SA. Chiu G, et al. Among authors: li s. Bioorg Med Chem Lett. 2008 Jan 15;18(2):640-4. doi: 10.1016/j.bmcl.2007.11.068. Epub 2007 Nov 22. Bioorg Med Chem Lett. 2008. PMID: 18055202

5

Folate analogues. 35. Synthesis and biological evaluation of 1-deaza, 3-deaza, and bridge-elongated analogues of N10-propargyl-5,8-dideazafolic acid.

Li SW, Nair MG, Edwards DM, Kisliuk RL, Gaumont Y, Dev IK, Duch DS, Humphreys J, Smith GK, Ferone R. Li SW, et al. J Med Chem. 1991 Sep;34(9):2746-54. doi: 10.1021/jm00113a011. J Med Chem. 1991. PMID: 1895294

6

(Arylpiperazinyl)cyclohexylsufonamides: discovery of alpha(1a/1d)-selective adrenergic receptor antagonists for the treatment of Benign Prostatic Hyperplasia/Lower Urinary Tract Symptoms (BPH/LUTS).

Chiu G, Li S, Connolly PJ, Pulito V, Liu J, Middleton SA. Chiu G, et al. Among authors: li s. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3292-7. doi: 10.1016/j.bmcl.2007.04.008. Epub 2007 Apr 10. Bioorg Med Chem Lett. 2007. PMID: 17452102

7

Aminocyclohexylsulfonamides: discovery of metabolically stable alpha(1a/1d)-selective adrenergic receptor antagonists for the treatment of benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS).

Chiu G, Li S, Cai H, Connolly PJ, Peng S, Stauber K, Pulito V, Liu J, Middleton SA. Chiu G, et al. Among authors: li s. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6123-8. doi: 10.1016/j.bmcl.2007.09.051. Epub 2007 Sep 18. Bioorg Med Chem Lett. 2007. PMID: 17904840

8

Synthesis and evaluation of pyrazolo[3,4-b]pyridine CDK1 inhibitors as anti-tumor agents.

Lin R, Connolly PJ, Lu Y, Chiu G, Li S, Yu Y, Huang S, Li X, Emanuel SL, Middleton SA, Gruninger RH, Adams M, Fuentes-Pesquera AR, Greenberger LM. Lin R, et al. Among authors: li s, li x. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4297-302. doi: 10.1016/j.bmcl.2007.05.029. Epub 2007 May 16. Bioorg Med Chem Lett. 2007. PMID: 17532631

9

Design, synthesis, and evaluation of 3,4-disubstituted pyrazole analogues as anti-tumor CDK inhibitors.

Lin R, Chiu G, Yu Y, Connolly PJ, Li S, Lu Y, Adams M, Fuentes-Pesquera AR, Emanuel SL, Greenberger LM. Lin R, et al. Among authors: li s. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4557-61. doi: 10.1016/j.bmcl.2007.05.092. Epub 2007 Jun 6. Bioorg Med Chem Lett. 2007. PMID: 17574416

10

1-Arylpiperazinyl-4-cyclohexylamine derived isoindole-1,3-diones as potent and selective alpha-1a/1d adrenergic receptor ligands.

Li S, Chiu G, Pulito VL, Liu J, Connolly PJ, Middleton SA. Li S, et al. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1646-50. doi: 10.1016/j.bmcl.2006.12.111. Epub 2007 Jan 12. Bioorg Med Chem Lett. 2007. PMID: 17254786

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